DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classNGT
GeneSetELECTRON_TRANSPORT_CHAIN
Enrichment Score (ES)0.6074125
Normalized Enrichment Score (NES)1.739312
Nominal p-value0.033797216
FDR q-value0.2114812
FWER p-Value0.481
Table: GSEA Results Summary



Fig 1: Enrichment plot: ELECTRON_TRANSPORT_CHAIN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NDUFA2NDUFA2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa712.6400.0241Yes
2NDUFB2NDUFB2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa822.5750.0521Yes
3COX7A1COX7A1
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)972.5060.0790Yes
4ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)1552.2850.1002Yes
5NDUFB6NDUFB6
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa1672.2510.1244Yes
6ATP5EATP5E
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit1812.2320.1484Yes
7NDUFS5NDUFS5
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)2162.1670.1700Yes
8NDUFB1NDUFB1
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa2342.1430.1926Yes
9NDUFB8NDUFB8
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa2502.1170.2151Yes
10COX7CCOX7C
Entrez,  Source
cytochrome c oxidase subunit VIIc2892.0600.2352Yes
11UQCRUQCR
Entrez,  Source
ubiquinol-cytochrome c reductase, 6.4kDa subunit3012.0300.2570Yes
12ATP5LATP5L
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G3102.0220.2790Yes
13COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb3232.0010.3004Yes
14ATP5IATP5I
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E3651.9440.3190Yes
15ATP5SATP5S
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)3691.9390.3404Yes
16NDUFA7NDUFA7
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa3831.9130.3607Yes
17COX7A2COX7A2
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)4801.8110.3737Yes
18NDUFA10NDUFA10
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa7691.6250.3701Yes
19NDUFS6NDUFS6
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)8261.5970.3837Yes
20NDUFS8NDUFS8
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)8631.5760.3985Yes
21UQCRBUQCRB
Entrez,  Source
ubiquinol-cytochrome c reductase binding protein9091.5420.4123Yes
22COX6CCOX6C
Entrez,  Source
cytochrome c oxidase subunit VIc9291.5320.4280Yes
23NDUFA6NDUFA6
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa9551.5160.4430Yes
24NDUFC1NDUFC1
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa9621.5130.4595Yes
25COX7A2LCOX7A2L
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 2 like10021.4940.4732Yes
26NDUFA3NDUFA3
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa10181.4880.4886Yes
27ATP5HATP5H
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d10891.4560.4996Yes
28ATP5J2ATP5J2
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F210971.4540.5153Yes
29SLC25A5SLC25A5
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 511531.4310.5271Yes
30NDUFB5NDUFB5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa11811.4220.5409Yes
31NDUFAB1NDUFAB1
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa13681.3360.5418Yes
32COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 113951.3260.5546Yes
33NDUFA8NDUFA8
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa15591.2570.5563Yes
34ATP5F1ATP5F1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B115951.2450.5676Yes
35COX4I1COX4I1
Entrez,  Source
cytochrome c oxidase subunit IV isoform 119011.1340.5572Yes
36NDUFS7NDUFS7
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)19801.1090.5637Yes
37SDHBSDHB
Entrez,  Source
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)20431.0880.5711Yes
38NDUFA4NDUFA4
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa20511.0860.5827Yes
39COX11COX11
Entrez,  Source
COX11 homolog, cytochrome c oxidase assembly protein (yeast)21641.0530.5860Yes
40ATP5DATP5D
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit22251.0340.5930Yes
41ATPIF1ATPIF1
Entrez,  Source
ATPase inhibitory factor 123301.0010.5963Yes
42UQCRHUQCRH
Entrez,  Source
ubiquinol-cytochrome c reductase hinge protein23950.9770.6024Yes
43NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)24770.9560.6069Yes
44COX5BCOX5B
Entrez,  Source
cytochrome c oxidase subunit Vb28180.8660.5909Yes
45SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa28610.8550.5973Yes
46NDUFB7NDUFB7
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa29120.8420.6029Yes
47UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 130100.8200.6047Yes
48NDUFB3NDUFB3
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa30940.8030.6074Yes
49SLC25A14SLC25A14
Entrez,  Source
solute carrier family 25 (mitochondrial carrier, brain), member 1432550.7600.6038No
50NDUFV2NDUFV2
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa34040.7210.6007No
51SLC25A6SLC25A6
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 637360.6500.5829No
52ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)38030.6350.5850No
53NDUFV1NDUFV1
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa38670.6210.5872No
54SURF1SURF1
Entrez,  Source
surfeit 138910.6180.5924No
55AFG3L2AFG3L2
Entrez,  Source
AFG3 ATPase family gene 3-like 2 (yeast)39470.6080.5950No
56ATP5G1ATP5G1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)39780.6030.5995No
57ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F640860.5810.5979No
58CYCSCYCS
Entrez,  Source
cytochrome c, somatic41780.5620.5973No
59COX5ACOX5A
Entrez,  Source
cytochrome c oxidase subunit Va45130.4970.5776No
60ATP5C1ATP5C1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 145170.4970.5829No
61COX15COX15
Entrez,  Source
COX15 homolog, cytochrome c oxidase assembly protein (yeast)51800.3650.5370No
62NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)55800.2870.5101No
63NDUFS3NDUFS3
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)57100.2620.5032No
64NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa57730.2520.5014No
65NDUFA9NDUFA9
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa61980.1740.4713No
66SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein65830.1030.4434No
67UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II66240.0950.4415No
68NDUFC2NDUFC2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa7516-0.0730.3750No
69POPDC2POPDC2
Entrez,  Source
popeye domain containing 27620-0.0960.3683No
70NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)7828-0.1340.3542No
71UCP1UCP1
Entrez,  Source
uncoupling protein 1 (mitochondrial, proton carrier)7854-0.1390.3538No
72ATP5G2ATP5G2
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)7914-0.1540.3511No
73ATP5BATP5B
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide8037-0.1760.3438No
74SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 48562-0.2780.3074No
75SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)8570-0.2800.3100No
76UCP3UCP3
Entrez,  Source
uncoupling protein 3 (mitochondrial, proton carrier)8618-0.2880.3096No
77COX6A2COX6A2
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 29081-0.3910.2791No
78UCP2UCP2
Entrez,  Source
uncoupling protein 2 (mitochondrial, proton carrier)10921-0.8450.1496No
79UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I11184-0.9260.1402No
80ATP5A1ATP5A1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle12943-1.8880.0285No
Table: GSEA details [plain text format]



Fig 2: ELECTRON_TRANSPORT_CHAIN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ELECTRON_TRANSPORT_CHAIN: Random ES distribution   
Gene set null distribution of ES for ELECTRON_TRANSPORT_CHAIN