DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classDMT
GeneSetST_MONOCYTE_AD_PATHWAY
Enrichment Score (ES)-0.47710598
Normalized Enrichment Score (NES)-1.529905
Nominal p-value0.033864543
FDR q-value1.0
FWER p-Value0.919
Table: GSEA Results Summary



Fig 1: Enrichment plot: ST_MONOCYTE_AD_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DLG4DLG4
Entrez,  Source
discs, large homolog 4 (Drosophila)20481.087-0.1021No
2KCNJ3KCNJ3
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 322211.035-0.0655No
3PTX3PTX3
Entrez,  Source
pentraxin-related gene, rapidly induced by IL-1 beta28440.860-0.0712No
4AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 128690.853-0.0322No
5KCNJ5KCNJ5
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 532290.767-0.0226No
6CAV3CAV3
Entrez,  Source
caveolin 360590.201-0.2258No
7ASAH1ASAH1
Entrez,  Source
N-acylsphingosine amidohydrolase (acid ceramidase) 167270.078-0.2722No
8RAC1RAC1
Entrez,  Source
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)67970.064-0.2743No
9GNAQGNAQ
Entrez,  Source
guanine nucleotide binding protein (G protein), q polypeptide7184-0.009-0.3029No
10RYR1RYR1
Entrez,  Source
ryanodine receptor 1 (skeletal)7220-0.015-0.3049No
11CAMPCAMP
Entrez,  Source
cathelicidin antimicrobial peptide8536-0.273-0.3907No
12ITPR2ITPR2
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 29636-0.511-0.4489Yes
13PITX2PITX2
Entrez,  Source
paired-like homeodomain transcription factor 210012-0.597-0.4486Yes
14ITPR3ITPR3
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 310111-0.621-0.4263Yes
15ADRB1ADRB1
Entrez,  Source
adrenergic, beta-1-, receptor10516-0.726-0.4220Yes
16ITPR1ITPR1
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 110812-0.808-0.4055Yes
17GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 111271-0.954-0.3944Yes
18MAPK1MAPK1
Entrez,  Source
mitogen-activated protein kinase 111721-1.127-0.3743Yes
19EPHB2EPHB2
Entrez,  Source
EPH receptor B211875-1.192-0.3288Yes
20HTATIPHTATIP
Entrez,  Source
HIV-1 Tat interacting protein, 60kDa11957-1.229-0.2762Yes
21KCNJ9KCNJ9
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 912182-1.335-0.2293Yes
22RHORHO
Entrez,  Source
rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant)13007-1.971-0.1970Yes
23DAG1DAG1
Entrez,  Source
dystroglycan 1 (dystrophin-associated glycoprotein 1)13133-2.182-0.1021Yes
24APCAPC
Entrez,  Source
adenomatosis polyposis coli13227-2.4300.0070Yes
Table: GSEA details [plain text format]



Fig 2: ST_MONOCYTE_AD_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ST_MONOCYTE_AD_PATHWAY: Random ES distribution   
Gene set null distribution of ES for ST_MONOCYTE_AD_PATHWAY