Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
| Phenotype | Diabetes.cls#NGT_versus_DMT |
| Upregulated in class | NGT |
| GeneSet | ANDROGEN_UP_GENES |
| Enrichment Score (ES) | 0.32306373 |
| Normalized Enrichment Score (NES) | 1.2659323 |
| Nominal p-value | 0.10816327 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 273 | 2.094 | 0.0241 | Yes |
| 2 | ANKH | ANKH Entrez, Source | ankylosis, progressive homolog (mouse) | 579 | 1.736 | 0.0382 | Yes |
| 3 | DNAJB9 | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 637 | 1.707 | 0.0703 | Yes |
| 4 | DCTN3 | DCTN3 Entrez, Source | dynactin 3 (p22) | 693 | 1.672 | 0.1018 | Yes |
| 5 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 726 | 1.651 | 0.1347 | Yes |
| 6 | SLC26A2 | SLC26A2 Entrez, Source | solute carrier family 26 (sulfate transporter), member 2 | 999 | 1.495 | 0.1461 | Yes |
| 7 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 1063 | 1.471 | 0.1727 | Yes |
| 8 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 1315 | 1.362 | 0.1829 | Yes |
| 9 | CAMKK2 | CAMKK2 Entrez, Source | calcium/calmodulin-dependent protein kinase kinase 2, beta | 1481 | 1.289 | 0.1979 | Yes |
| 10 | MERTK | MERTK Entrez, Source | c-mer proto-oncogene tyrosine kinase | 1485 | 1.285 | 0.2252 | Yes |
| 11 | GSR | GSR Entrez, Source | glutathione reductase | 1588 | 1.248 | 0.2441 | Yes |
| 12 | LIFR | LIFR Entrez, Source | leukemia inhibitory factor receptor alpha | 1631 | 1.231 | 0.2672 | Yes |
| 13 | TPD52 | TPD52 Entrez, Source | tumor protein D52 | 1930 | 1.125 | 0.2688 | Yes |
| 14 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 2123 | 1.067 | 0.2770 | Yes |
| 15 | CPD | CPD Entrez, Source | carboxypeptidase D | 2357 | 0.990 | 0.2806 | Yes |
| 16 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 2422 | 0.970 | 0.2965 | Yes |
| 17 | UAP1 | UAP1 Entrez, Source | UDP-N-acteylglucosamine pyrophosphorylase 1 | 2815 | 0.866 | 0.2854 | Yes |
| 18 | RBM10 | RBM10 Entrez, Source | RNA binding motif protein 10 | 3228 | 0.767 | 0.2707 | Yes |
| 19 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 3286 | 0.751 | 0.2825 | Yes |
| 20 | KLK3 | KLK3 Entrez, Source | kallikrein 3, (prostate specific antigen) | 3388 | 0.725 | 0.2903 | Yes |
| 21 | AZGP1 | AZGP1 Entrez, Source | alpha-2-glycoprotein 1, zinc | 3500 | 0.702 | 0.2969 | Yes |
| 22 | SRP19 | SRP19 Entrez, Source | signal recognition particle 19kDa | 3591 | 0.685 | 0.3048 | Yes |
| 23 | TMEPAI | TMEPAI Entrez, Source | transmembrane, prostate androgen induced RNA | 3697 | 0.663 | 0.3110 | Yes |
| 24 | B2M | B2M Entrez, Source | beta-2-microglobulin | 3723 | 0.654 | 0.3231 | Yes |
| 25 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 4036 | 0.590 | 0.3121 | No |
| 26 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 4137 | 0.569 | 0.3167 | No |
| 27 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 4620 | 0.475 | 0.2905 | No |
| 28 | INPP4B | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4664 | 0.463 | 0.2972 | No |
| 29 | SNAP25 | SNAP25 Entrez, Source | synaptosomal-associated protein, 25kDa | 4665 | 0.462 | 0.3070 | No |
| 30 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 4736 | 0.448 | 0.3113 | No |
| 31 | HERC3 | HERC3 Entrez, Source | hect domain and RLD 3 | 4904 | 0.414 | 0.3076 | No |
| 32 | ABCC4 | ABCC4 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 4954 | 0.407 | 0.3125 | No |
| 33 | SMS | SMS Entrez, Source | spermine synthase | 5151 | 0.370 | 0.3057 | No |
| 34 | ALDH1A3 | ALDH1A3 Entrez, Source | aldehyde dehydrogenase 1 family, member A3 | 6290 | 0.158 | 0.2232 | No |
| 35 | KLK2 | KLK2 Entrez, Source | kallikrein 2, prostatic | 6955 | 0.033 | 0.1739 | No |
| 36 | H1F0 | H1F0 Entrez, Source | H1 histone family, member 0 | 7447 | -0.059 | 0.1381 | No |
| 37 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 7859 | -0.139 | 0.1101 | No |
| 38 | ELL2 | ELL2 Entrez, Source | elongation factor, RNA polymerase II, 2 | 8104 | -0.189 | 0.0957 | No |
| 39 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 8515 | -0.268 | 0.0705 | No |
| 40 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 8809 | -0.327 | 0.0554 | No |
| 41 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 9026 | -0.379 | 0.0472 | No |
| 42 | SORD | SORD Entrez, Source | sorbitol dehydrogenase | 9388 | -0.459 | 0.0298 | No |
| 43 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 9474 | -0.476 | 0.0336 | No |
| 44 | GUCY1A3 | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 9515 | -0.483 | 0.0409 | No |
| 45 | IQGAP2 | IQGAP2 Entrez, Source | IQ motif containing GTPase activating protein 2 | 9530 | -0.488 | 0.0502 | No |
| 46 | ITGAV | ITGAV Entrez, Source | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 10132 | -0.625 | 0.0183 | No |
| 47 | ADRM1 | ADRM1 Entrez, Source | adhesion regulating molecule 1 | 10257 | -0.658 | 0.0229 | No |
| 48 | B4GALT1 | B4GALT1 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 10397 | -0.691 | 0.0272 | No |
| 49 | SEC24D | SEC24D Entrez, Source | SEC24 related gene family, member D (S. cerevisiae) | 10726 | -0.784 | 0.0192 | No |
| 50 | KRT19 | KRT19 Entrez, Source | keratin 19 | 10771 | -0.794 | 0.0328 | No |
| 51 | TMPRSS2 | TMPRSS2 Entrez, Source | transmembrane protease, serine 2 | 10953 | -0.852 | 0.0374 | No |
| 52 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 11030 | -0.876 | 0.0504 | No |
| 53 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 11185 | -0.926 | 0.0585 | No |
| 54 | LMAN1 | LMAN1 Entrez, Source | lectin, mannose-binding, 1 | 11488 | -1.034 | 0.0578 | No |
| 55 | PTPN21 | PTPN21 Entrez, Source | protein tyrosine phosphatase, non-receptor type 21 | 11787 | -1.157 | 0.0601 | No |
| 56 | VAPA | VAPA Entrez, Source | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 12036 | -1.263 | 0.0683 | No |
| 57 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 12174 | -1.331 | 0.0864 | No |
