DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classDMT
GeneSetMAP00120_BILE_ACID_BIOSYNTHESIS
Enrichment Score (ES)-0.5251498
Normalized Enrichment Score (NES)-1.7571636
Nominal p-value0.0019157088
FDR q-value0.8698195
FWER p-Value0.403
Table: GSEA Results Summary



Fig 1: Enrichment plot: MAP00120_BILE_ACID_BIOSYNTHESIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ADH5ADH5
Entrez,  Source
alcohol dehydrogenase 5 (class III), chi polypeptide17491.182-0.0617No
2LIPALIPA
Entrez,  Source
lipase A, lysosomal acid, cholesterol esterase (Wolman disease)27020.894-0.0805No
3SRD5A1SRD5A1
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)35400.695-0.1024No
4ADH1BADH1B
Entrez,  Source
alcohol dehydrogenase IB (class I), beta polypeptide45760.486-0.1515No
5ALDH3A2ALDH3A2
Entrez,  Source
aldehyde dehydrogenase 3 family, member A248050.435-0.1429No
6SOAT1SOAT1
Entrez,  Source
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 161140.189-0.2301No
7SRD5A2SRD5A2
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)64530.126-0.2481No
8BAATBAAT
Entrez,  Source
bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)65070.118-0.2451No
9AKR1D1AKR1D1
Entrez,  Source
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)66330.094-0.2489No
10CYP7A1CYP7A1
Entrez,  Source
cytochrome P450, family 7, subfamily A, polypeptide 170600.013-0.2802No
11ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)7404-0.050-0.3030No
12ACAA1ACAA1
Entrez,  Source
acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase)8666-0.296-0.3803No
13ALDH1A1ALDH1A1
Entrez,  Source
aldehyde dehydrogenase 1 family, member A19254-0.428-0.3992No
14ALDH1B1ALDH1B1
Entrez,  Source
aldehyde dehydrogenase 1 family, member B110207-0.645-0.4327No
15CELCEL
Entrez,  Source
carboxyl ester lipase (bile salt-stimulated lipase)11301-0.966-0.4579Yes
16ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)12197-1.344-0.4458Yes
17HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit12208-1.349-0.3669Yes
18ADH7ADH7
Entrez,  Source
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide12287-1.401-0.2901Yes
19CYP27A1CYP27A1
Entrez,  Source
cytochrome P450, family 27, subfamily A, polypeptide 112996-1.961-0.2276Yes
20ADH1AADH1A
Entrez,  Source
alcohol dehydrogenase 1A (class I), alpha polypeptide13083-2.079-0.1112Yes
21ADH6ADH6
Entrez,  Source
alcohol dehydrogenase 6 (class V)13134-2.1850.0140Yes
Table: GSEA details [plain text format]



Fig 2: MAP00120_BILE_ACID_BIOSYNTHESIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: MAP00120_BILE_ACID_BIOSYNTHESIS: Random ES distribution   
Gene set null distribution of ES for MAP00120_BILE_ACID_BIOSYNTHESIS