DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classDMT
GeneSetINTEGRINPATHWAY
Enrichment Score (ES)-0.45898736
Normalized Enrichment Score (NES)-1.4405193
Nominal p-value0.07952286
FDR q-value1.0
FWER p-Value0.986
Table: GSEA Results Summary



Fig 1: Enrichment plot: INTEGRINPATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1HRASHRAS
Entrez,  Source
v-Ha-ras Harvey rat sarcoma viral oncogene homolog18821.139-0.0915No
2RAP1ARAP1A
Entrez,  Source
RAP1A, member of RAS oncogene family22541.024-0.0744No
3PPP1R12BPPP1R12B
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12B34060.721-0.1292No
4CSKCSK
Entrez,  Source
c-src tyrosine kinase52600.351-0.2532No
5PXNPXN
Entrez,  Source
paxillin52630.351-0.2379No
6JUNJUN
Entrez,  Source
jun oncogene55150.296-0.2438No
7TLN1TLN1
Entrez,  Source
talin 162190.171-0.2892No
8MAPK8MAPK8
Entrez,  Source
mitogen-activated protein kinase 862920.157-0.2877No
9BCRBCR
Entrez,  Source
breakpoint cluster region66810.086-0.3131No
10SHC1SHC1
Entrez,  Source
SHC (Src homology 2 domain containing) transforming protein 17655-0.101-0.3819No
11SOS1SOS1
Entrez,  Source
son of sevenless homolog 1 (Drosophila)7737-0.114-0.3829No
12CRKLCRKL
Entrez,  Source
v-crk sarcoma virus CT10 oncogene homolog (avian)-like7995-0.169-0.3948No
13PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 28233-0.216-0.4032No
14ACTN1ACTN1
Entrez,  Source
actinin, alpha 18809-0.327-0.4320No
15SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)9168-0.408-0.4410Yes
16MAP2K2MAP2K2
Entrez,  Source
mitogen-activated protein kinase kinase 29313-0.442-0.4324Yes
17RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 19350-0.450-0.4153Yes
18GRB2GRB2
Entrez,  Source
growth factor receptor-bound protein 29614-0.507-0.4128Yes
19CAV1CAV1
Entrez,  Source
caveolin 1, caveolae protein, 22kDa9659-0.518-0.3934Yes
20ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 19719-0.533-0.3743Yes
21FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES9831-0.555-0.3582Yes
22ZYXZYX
Entrez,  Source
zyxin10519-0.726-0.3780Yes
23ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle10699-0.776-0.3573Yes
24ACTN3ACTN3
Entrez,  Source
actinin, alpha 311022-0.874-0.3431Yes
25ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)11447-1.020-0.3301Yes
26CAPN1CAPN1
Entrez,  Source
calpain 1, (mu/I) large subunit11691-1.113-0.2994Yes
27MAPK1MAPK1
Entrez,  Source
mitogen-activated protein kinase 111721-1.127-0.2520Yes
28MAPK3MAPK3
Entrez,  Source
mitogen-activated protein kinase 311781-1.155-0.2056Yes
29MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 111928-1.218-0.1630Yes
30VCLVCL
Entrez,  Source
vinculin12776-1.739-0.1502Yes
31ACTN2ACTN2
Entrez,  Source
actinin, alpha 212864-1.813-0.0769Yes
32CAPNS1CAPNS1
Entrez,  Source
calpain, small subunit 113253-2.5270.0050Yes
Table: GSEA details [plain text format]



Fig 2: INTEGRINPATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: INTEGRINPATHWAY: Random ES distribution   
Gene set null distribution of ES for INTEGRINPATHWAY