Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | DMT |
GeneSet | WNTPATHWAY |
Enrichment Score (ES) | -0.4347178 |
Normalized Enrichment Score (NES) | -1.3887875 |
Nominal p-value | 0.11895161 |
FDR q-value | 1.0 |
FWER p-Value | 0.996 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | HDAC1 | HDAC1 Entrez,  Source | histone deacetylase 1 | 1021 | 1.487 | 0.0026 | No |
2 | WNT1 | WNT1 Entrez,  Source | wingless-type MMTV integration site family, member 1 | 2674 | 0.902 | -0.0735 | No |
3 | FZD1 | FZD1 Entrez,  Source | frizzled homolog 1 (Drosophila) | 2711 | 0.893 | -0.0285 | No |
4 | BTRC | BTRC Entrez,  Source | beta-transducin repeat containing | 3106 | 0.799 | -0.0155 | No |
5 | TLE1 | TLE1 Entrez,  Source | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 3916 | 0.613 | -0.0436 | No |
6 | CSNK1A1 | CSNK1A1 Entrez,  Source | casein kinase 1, alpha 1 | 4348 | 0.530 | -0.0478 | No |
7 | CCND1 | CCND1 Entrez,  Source | cyclin D1 | 5148 | 0.370 | -0.0881 | No |
8 | CSNK1D | CSNK1D Entrez,  Source | casein kinase 1, delta | 6586 | 0.102 | -0.1907 | No |
9 | MAP3K7 | MAP3K7 Entrez,  Source | mitogen-activated protein kinase kinase kinase 7 | 7018 | 0.022 | -0.2220 | No |
10 | PPP2CA | PPP2CA Entrez,  Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 7126 | 0.002 | -0.2299 | No |
11 | GSK3B | GSK3B Entrez,  Source | glycogen synthase kinase 3 beta | 7477 | -0.065 | -0.2527 | No |
12 | WIF1 | WIF1 Entrez,  Source | WNT inhibitory factor 1 | 7818 | -0.132 | -0.2713 | No |
13 | CTBP1 | CTBP1 Entrez,  Source | C-terminal binding protein 1 | 8298 | -0.227 | -0.2952 | No |
14 | FRAT1 | FRAT1 Entrez,  Source | frequently rearranged in advanced T-cell lymphomas | 8679 | -0.299 | -0.3078 | No |
15 | MYC | MYC Entrez,  Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 8724 | -0.312 | -0.2944 | No |
16 | TCF1 | TCF1 Entrez,  Source | transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor | 9207 | -0.417 | -0.3084 | No |
17 | CSNK2A1 | CSNK2A1 Entrez,  Source | casein kinase 2, alpha 1 polypeptide | 10887 | -0.837 | -0.3900 | Yes |
18 | PPARD | PPARD Entrez,  Source | peroxisome proliferative activated receptor, delta | 11053 | -0.883 | -0.3553 | Yes |
19 | AXIN1 | AXIN1 Entrez,  Source | axin 1 | 11236 | -0.943 | -0.3187 | Yes |
20 | MAP3K7IP1 | MAP3K7IP1 Entrez,  Source | mitogen-activated protein kinase kinase kinase 7 interacting protein 1 | 11639 | -1.092 | -0.2906 | Yes |
21 | NLK | NLK Entrez,  Source | nemo-like kinase | 11837 | -1.176 | -0.2426 | Yes |
22 | CTNNB1 | CTNNB1 Entrez,  Source | catenin (cadherin-associated protein), beta 1, 88kDa | 12139 | -1.311 | -0.1953 | Yes |
23 | DVL1 | DVL1 Entrez,  Source | dishevelled, dsh homolog 1 (Drosophila) | 12295 | -1.403 | -0.1320 | Yes |
24 | CREBBP | CREBBP Entrez,  Source | CREB binding protein (Rubinstein-Taybi syndrome) | 12434 | -1.485 | -0.0631 | Yes |
25 | APC | APC Entrez,  Source | adenomatosis polyposis coli | 13227 | -2.430 | 0.0070 | Yes |