Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | DMT |
GeneSet | MCALPAINPATHWAY |
Enrichment Score (ES) | -0.47667816 |
Normalized Enrichment Score (NES) | -1.4912983 |
Nominal p-value | 0.05212355 |
FDR q-value | 1.0 |
FWER p-Value | 0.96 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | HRAS | HRAS Entrez,  Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 1882 | 1.139 | -0.0745 | No |
2 | CAPN2 | CAPN2 Entrez,  Source | calpain 2, (m/II) large subunit | 3523 | 0.698 | -0.1568 | No |
3 | PRKAR2B | PRKAR2B Entrez,  Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 3733 | 0.651 | -0.1342 | No |
4 | PRKAR2A | PRKAR2A Entrez,  Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 4724 | 0.450 | -0.1821 | No |
5 | PXN | PXN Entrez,  Source | paxillin | 5263 | 0.351 | -0.2019 | No |
6 | PRKACG | PRKACG Entrez,  Source | protein kinase, cAMP-dependent, catalytic, gamma | 5424 | 0.313 | -0.1955 | No |
7 | EGFR | EGFR Entrez,  Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 5880 | 0.233 | -0.2160 | No |
8 | MYLK | MYLK Entrez,  Source | myosin, light chain kinase | 5992 | 0.211 | -0.2120 | No |
9 | PRKACB | PRKACB Entrez,  Source | protein kinase, cAMP-dependent, catalytic, beta | 5998 | 0.210 | -0.2000 | No |
10 | TLN1 | TLN1 Entrez,  Source | talin 1 | 6219 | 0.171 | -0.2065 | No |
11 | EGF | EGF Entrez,  Source | epidermal growth factor (beta-urogastrone) | 6502 | 0.119 | -0.2207 | No |
12 | PTK2 | PTK2 Entrez,  Source | PTK2 protein tyrosine kinase 2 | 8233 | -0.216 | -0.3381 | No |
13 | CXCR3 | CXCR3 Entrez,  Source | chemokine (C-X-C motif) receptor 3 | 9375 | -0.456 | -0.3970 | No |
14 | VIL2 | VIL2 Entrez,  Source | villin 2 (ezrin) | 10435 | -0.700 | -0.4355 | Yes |
15 | ACTA1 | ACTA1 Entrez,  Source | actin, alpha 1, skeletal muscle | 10699 | -0.776 | -0.4096 | Yes |
16 | MYL2 | MYL2 Entrez,  Source | myosin, light chain 2, regulatory, cardiac, slow | 10890 | -0.837 | -0.3746 | Yes |
17 | ITGB1 | ITGB1 Entrez,  Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11447 | -1.020 | -0.3564 | Yes |
18 | CAPN1 | CAPN1 Entrez,  Source | calpain 1, (mu/I) large subunit | 11691 | -1.113 | -0.3091 | Yes |
19 | MAPK1 | MAPK1 Entrez,  Source | mitogen-activated protein kinase 1 | 11721 | -1.127 | -0.2450 | Yes |
20 | MAPK3 | MAPK3 Entrez,  Source | mitogen-activated protein kinase 3 | 11781 | -1.155 | -0.1815 | Yes |
21 | PRKAR1A | PRKAR1A Entrez,  Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 13252 | -2.521 | -0.1436 | Yes |
22 | CAPNS1 | CAPNS1 Entrez,  Source | calpain, small subunit 1 | 13253 | -2.527 | 0.0050 | Yes |