DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classNGT
GeneSetVOXPHOS
Enrichment Score (ES)0.61596334
Normalized Enrichment Score (NES)1.8094529
Nominal p-value0.016096579
FDR q-value0.15389146
FWER p-Value0.296
Table: GSEA Results Summary



Fig 1: Enrichment plot: VOXPHOS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NDUFA2NDUFA2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa712.6400.0247Yes
2NDUFB2NDUFB2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa822.5750.0532Yes
3COX7A1COX7A1
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)972.5060.0807Yes
4ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)1552.2850.1024Yes
5NDUFB6NDUFB6
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa1672.2510.1272Yes
6ATP5EATP5E
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit1812.2320.1516Yes
7NDUFS5NDUFS5
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)2162.1670.1737Yes
8NDUFB1NDUFB1
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa2342.1430.1968Yes
9NDUFB8NDUFB8
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa2502.1170.2198Yes
10COX7CCOX7C
Entrez,  Source
cytochrome c oxidase subunit VIIc2892.0600.2403Yes
11UQCRUQCR
Entrez,  Source
ubiquinol-cytochrome c reductase, 6.4kDa subunit3012.0300.2626Yes
12ATP5LATP5L
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G3102.0220.2850Yes
13COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb3232.0010.3069Yes
14ATP5IATP5I
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E3651.9440.3259Yes
15NDUFA7NDUFA7
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa3831.9130.3464Yes
16COX7A2COX7A2
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)4801.8110.3597Yes
17NDUFA10NDUFA10
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa7691.6250.3565Yes
18NDUFS6NDUFS6
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)8261.5970.3704Yes
19NDUFS8NDUFS8
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)8631.5760.3857Yes
20UQCRBUQCRB
Entrez,  Source
ubiquinol-cytochrome c reductase binding protein9091.5420.3998Yes
21COX6CCOX6C
Entrez,  Source
cytochrome c oxidase subunit VIc9291.5320.4158Yes
22NDUFA6NDUFA6
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa9551.5160.4312Yes
23NDUFC1NDUFC1
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa9621.5130.4479Yes
24COX7A2LCOX7A2L
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 2 like10021.4940.4620Yes
25NDUFA3NDUFA3
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa10181.4880.4778Yes
26ATP5HATP5H
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d10891.4560.4891Yes
27ATP5J2ATP5J2
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F210971.4540.5051Yes
28NDUFB5NDUFB5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa11811.4220.5150Yes
29NDUFAB1NDUFAB1
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa13681.3360.5162Yes
30COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 113951.3260.5293Yes
31NGFRAP1NGFRAP1
Entrez,  Source
nerve growth factor receptor (TNFRSF16) associated protein 114621.2980.5391Yes
32CYC1CYC1
Entrez,  Source
cytochrome c-115421.2620.5475Yes
33NDUFA8NDUFA8
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa15591.2570.5606Yes
34ATP5F1ATP5F1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B115951.2450.5721Yes
35COX4I1COX4I1
Entrez,  Source
cytochrome c oxidase subunit IV isoform 119011.1340.5620Yes
36NDUFS7NDUFS7
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)19801.1090.5687Yes
37SDHBSDHB
Entrez,  Source
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)20431.0880.5764Yes
38NDUFA4NDUFA4
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa20511.0860.5882Yes
39PET112LPET112L
Entrez,  Source
PET112-like (yeast)20621.0840.5998Yes
40COX11COX11
Entrez,  Source
COX11 homolog, cytochrome c oxidase assembly protein (yeast)21641.0530.6042Yes
41ATP5DATP5D
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit22251.0340.6114Yes
42UQCRHUQCRH
Entrez,  Source
ubiquinol-cytochrome c reductase hinge protein23950.9770.6098Yes
43NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)24770.9560.6145Yes
44COX5BCOX5B
Entrez,  Source
cytochrome c oxidase subunit Vb28180.8660.5987Yes
45SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa28610.8550.6053Yes
46NDUFB7NDUFB7
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa29120.8420.6111Yes
47UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 130100.8200.6131Yes
48NDUFB3NDUFB3
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa30940.8030.6160Yes
49ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)38030.6350.5697No
50SURF1SURF1
Entrez,  Source
surfeit 138910.6180.5702No
51ATP5G1ATP5G1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)39780.6030.5706No
52ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F640860.5810.5691No
53COX10COX10
Entrez,  Source
COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)40960.5790.5750No
54CYCSCYCS
Entrez,  Source
cytochrome c, somatic41780.5620.5753No
55COX5ACOX5A
Entrez,  Source
cytochrome c oxidase subunit Va45130.4970.5557No
56ATP5C1ATP5C1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 145170.4970.5612No
57SURF2SURF2
Entrez,  Source
surfeit 251610.3680.5168No
58COX15COX15
Entrez,  Source
COX15 homolog, cytochrome c oxidase assembly protein (yeast)51800.3650.5196No
59CNOT7CNOT7
Entrez,  Source
CCR4-NOT transcription complex, subunit 753000.3420.5145No
60NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)55800.2870.4967No
61NDUFS3NDUFS3
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)57100.2620.4899No
62NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa57730.2520.4881No
63NDUFA9NDUFA9
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa61980.1740.4581No
64MBD3MBD3
Entrez,  Source
methyl-CpG binding domain protein 362430.1660.4567No
65SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein65830.1030.4322No
66UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II66240.0950.4303No
67NDUFC2NDUFC2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa7516-0.0730.3639No
68NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)7828-0.1340.3419No
69ATP5G2ATP5G2
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)7914-0.1540.3372No
70ATP5BATP5B
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide8037-0.1760.3300No
71SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)8570-0.2800.2931No
72COX6A2COX6A2
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 29081-0.3910.2590No
73BCL2L1BCL2L1
Entrez,  Source
BCL2-like 19561-0.4940.2285No
74CKAP1CKAP1
Entrez,  Source
cytoskeleton associated protein 19724-0.5340.2223No
75BCS1LBCS1L
Entrez,  Source
BCS1-like (yeast)10289-0.6640.1873No
76UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I11184-0.9260.1303No
77NFKBIL2NFKBIL2
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 213279-2.7150.0031No
Table: GSEA details [plain text format]



Fig 2: VOXPHOS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VOXPHOS: Random ES distribution   
Gene set null distribution of ES for VOXPHOS