DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classNGT
GeneSetHTERT_DOWN
Enrichment Score (ES)0.31193402
Normalized Enrichment Score (NES)1.2507424
Nominal p-value0.14398421
FDR q-value1.0
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: HTERT_DOWN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)1552.2850.0355Yes
2GSTO1GSTO1
Entrez,  Source
glutathione S-transferase omega 11782.2380.0800Yes
3NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)1992.1920.1238Yes
4TUBB4TUBB4
Entrez,  Source
tubulin, beta 46041.7250.1289Yes
5DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 66171.7170.1635Yes
6RAB11ARAB11A
Entrez,  Source
RAB11A, member RAS oncogene family8691.5700.1769Yes
7TCF4TCF4
Entrez,  Source
transcription factor 49571.5150.2017Yes
8CCNG1CCNG1
Entrez,  Source
cyclin G19811.5050.2310Yes
9EHHADHEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase11541.4300.2476Yes
10ACLYACLY
Entrez,  Source
ATP citrate lyase12681.3840.2676Yes
11TNFSF9TNFSF9
Entrez,  Source
tumor necrosis factor (ligand) superfamily, member 915781.2520.2701Yes
12TNFSF10TNFSF10
Entrez,  Source
tumor necrosis factor (ligand) superfamily, member 1016661.2190.2887Yes
13TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)22141.0360.2689Yes
14DNA2LDNA2L
Entrez,  Source
DNA2 DNA replication helicase 2-like (yeast)24710.9590.2694Yes
15PGFPGF
Entrez,  Source
placental growth factor, vascular endothelial growth factor-related protein26300.9170.2764Yes
16FAHFAH
Entrez,  Source
fumarylacetoacetate hydrolase (fumarylacetoacetase)27680.8770.2842Yes
17CALML3CALML3
Entrez,  Source
calmodulin-like 328650.8540.2945Yes
18AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 128690.8530.3119Yes
19IDI1IDI1
Entrez,  Source
isopentenyl-diphosphate delta isomerase 132860.7510.2961No
20SRD5A1SRD5A1
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)35400.6950.2913No
21AKR1C3AKR1C3
Entrez,  Source
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)36090.6800.3003No
22AHCYAHCY
Entrez,  Source
S-adenosylhomocysteine hydrolase37500.6480.3031No
23KYNUKYNU
Entrez,  Source
kynureninase (L-kynurenine hydrolase)43290.5340.2705No
24HEABHEAB
Entrez,  Source
-44800.5060.2697No
25ALDH3A2ALDH3A2
Entrez,  Source
aldehyde dehydrogenase 3 family, member A248050.4350.2542No
26VAV2VAV2
Entrez,  Source
vav 2 oncogene52870.3440.2250No
27PON2PON2
Entrez,  Source
paraoxonase 254380.3100.2201No
28VSNL1VSNL1
Entrez,  Source
visinin-like 155020.3000.2215No
29CD47CD47
Entrez,  Source
CD47 molecule55220.2950.2262No
30IL1RNIL1RN
Entrez,  Source
interleukin 1 receptor antagonist55780.2870.2280No
31PCNAPCNA
Entrez,  Source
proliferating cell nuclear antigen59310.2210.2060No
32ANXA4ANXA4
Entrez,  Source
annexin A463700.1420.1759No
33TRADDTRADD
Entrez,  Source
TNFRSF1A-associated via death domain67030.0830.1526No
34ASAH1ASAH1
Entrez,  Source
N-acylsphingosine amidohydrolase (acid ceramidase) 167270.0780.1525No
35GM2AGM2A
Entrez,  Source
GM2 ganglioside activator69880.0260.1334No
36NME4NME4
Entrez,  Source
non-metastatic cells 4, protein expressed in7146-0.0010.1216No
37ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta8042-0.1760.0577No
38TAGLNTAGLN
Entrez,  Source
transgelin8333-0.2330.0407No
39DHCR24DHCR24
Entrez,  Source
24-dehydrocholesterol reductase8515-0.2680.0326No
40PMLPML
Entrez,  Source
promyelocytic leukemia8685-0.3010.0260No
41PCOLN3PCOLN3
Entrez,  Source
procollagen (type III) N-endopeptidase8710-0.3070.0306No
42ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 158961-0.3630.0192No
43SAA1SAA1
Entrez,  Source
serum amyloid A19291-0.4360.0034No
44SORDSORD
Entrez,  Source
sorbitol dehydrogenase9388-0.4590.0056No
45SERPING1SERPING1
Entrez,  Source
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)9427-0.4670.0124No
46GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)9459-0.4720.0198No
47PPP1R7PPP1R7
Entrez,  Source
protein phosphatase 1, regulatory subunit 79750-0.5390.0091No
48STAT4STAT4
Entrez,  Source
signal transducer and activator of transcription 49783-0.5470.0180No
49A2MA2M
Entrez,  Source
alpha-2-macroglobulin9798-0.5490.0282No
50ALDH7A1ALDH7A1
Entrez,  Source
aldehyde dehydrogenase 7 family, member A19901-0.5730.0324No
51RAB40BRAB40B
Entrez,  Source
RAB40B, member RAS oncogene family10023-0.6000.0356No
52CBR1CBR1
Entrez,  Source
carbonyl reductase 110025-0.6000.0480No
53PAMPAM
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase10328-0.6730.0391No
54FOSBFOSB
Entrez,  Source
FBJ murine osteosarcoma viral oncogene homolog B10773-0.7950.0220No
55ABRABR
Entrez,  Source
active BCR-related gene10866-0.8290.0322No
56PIK3R3PIK3R3
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)11061-0.8850.0358No
57GAMTGAMT
Entrez,  Source
guanidinoacetate N-methyltransferase11607-1.0800.0170No
58XRCC5XRCC5
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)12018-1.2550.0120No
59RRAGARRAGA
Entrez,  Source
Ras-related GTP binding A12156-1.3200.0289No
60UNC119UNC119
Entrez,  Source
unc-119 homolog (C. elegans)12330-1.4200.0452No
61UGP2UGP2
Entrez,  Source
UDP-glucose pyrophosphorylase 212341-1.4240.0738No
Table: GSEA details [plain text format]



Fig 2: HTERT_DOWN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HTERT_DOWN: Random ES distribution   
Gene set null distribution of ES for HTERT_DOWN