Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | DMT |
GeneSet | MAP00120_BILE_ACID_BIOSYNTHESIS |
Enrichment Score (ES) | -0.5251498 |
Normalized Enrichment Score (NES) | -1.7571636 |
Nominal p-value | 0.0019157088 |
FDR q-value | 0.8698195 |
FWER p-Value | 0.403 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | ADH5 | ADH5 Entrez,  Source | alcohol dehydrogenase 5 (class III), chi polypeptide | 1749 | 1.182 | -0.0617 | No |
2 | LIPA | LIPA Entrez,  Source | lipase A, lysosomal acid, cholesterol esterase (Wolman disease) | 2702 | 0.894 | -0.0805 | No |
3 | SRD5A1 | SRD5A1 Entrez,  Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 3540 | 0.695 | -0.1024 | No |
4 | ADH1B | ADH1B Entrez,  Source | alcohol dehydrogenase IB (class I), beta polypeptide | 4576 | 0.486 | -0.1515 | No |
5 | ALDH3A2 | ALDH3A2 Entrez,  Source | aldehyde dehydrogenase 3 family, member A2 | 4805 | 0.435 | -0.1429 | No |
6 | SOAT1 | SOAT1 Entrez,  Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 6114 | 0.189 | -0.2301 | No |
7 | SRD5A2 | SRD5A2 Entrez,  Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 6453 | 0.126 | -0.2481 | No |
8 | BAAT | BAAT Entrez,  Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 6507 | 0.118 | -0.2451 | No |
9 | AKR1D1 | AKR1D1 Entrez,  Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 6633 | 0.094 | -0.2489 | No |
10 | CYP7A1 | CYP7A1 Entrez,  Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 7060 | 0.013 | -0.2802 | No |
11 | ALDH2 | ALDH2 Entrez,  Source | aldehyde dehydrogenase 2 family (mitochondrial) | 7404 | -0.050 | -0.3030 | No |
12 | ACAA1 | ACAA1 Entrez,  Source | acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase) | 8666 | -0.296 | -0.3803 | No |
13 | ALDH1A1 | ALDH1A1 Entrez,  Source | aldehyde dehydrogenase 1 family, member A1 | 9254 | -0.428 | -0.3992 | No |
14 | ALDH1B1 | ALDH1B1 Entrez,  Source | aldehyde dehydrogenase 1 family, member B1 | 10207 | -0.645 | -0.4327 | No |
15 | CEL | CEL Entrez,  Source | carboxyl ester lipase (bile salt-stimulated lipase) | 11301 | -0.966 | -0.4579 | Yes |
16 | ACAA2 | ACAA2 Entrez,  Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 12197 | -1.344 | -0.4458 | Yes |
17 | HADHB | HADHB Entrez,  Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 12208 | -1.349 | -0.3669 | Yes |
18 | ADH7 | ADH7 Entrez,  Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 12287 | -1.401 | -0.2901 | Yes |
19 | CYP27A1 | CYP27A1 Entrez,  Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 12996 | -1.961 | -0.2276 | Yes |
20 | ADH1A | ADH1A Entrez,  Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 13083 | -2.079 | -0.1112 | Yes |
21 | ADH6 | ADH6 Entrez,  Source | alcohol dehydrogenase 6 (class V) | 13134 | -2.185 | 0.0140 | Yes |