Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | DMT |
GeneSet | TGF_BETA_SIGNALING_PATHWAY |
Enrichment Score (ES) | -0.4318179 |
Normalized Enrichment Score (NES) | -1.591629 |
Nominal p-value | 0.013487476 |
FDR q-value | 0.98279196 |
FWER p-Value | 0.828 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | TGFBR1 | TGFBR1 Entrez,  Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 690 | 1.674 | 0.0068 | No |
2 | TGFB1 | TGFB1 Entrez,  Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 931 | 1.531 | 0.0424 | No |
3 | SKIL | SKIL Entrez,  Source | SKI-like | 1488 | 1.283 | 0.0456 | No |
4 | STAT1 | STAT1 Entrez,  Source | signal transducer and activator of transcription 1, 91kDa | 2291 | 1.014 | 0.0208 | No |
5 | FST | FST Entrez,  Source | follistatin | 2580 | 0.930 | 0.0318 | No |
6 | FKBP1A | FKBP1A Entrez,  Source | FK506 binding protein 1A, 12kDa | 2656 | 0.909 | 0.0580 | No |
7 | NFKB1 | NFKB1 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 4261 | 0.547 | -0.0435 | No |
8 | SERPINE1 | SERPINE1 Entrez,  Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 4362 | 0.527 | -0.0326 | No |
9 | FOXH1 | FOXH1 Entrez,  Source | forkhead box H1 | 4801 | 0.435 | -0.0503 | No |
10 | LEF1 | LEF1 Entrez,  Source | lymphoid enhancer-binding factor 1 | 4899 | 0.414 | -0.0431 | No |
11 | SPP1 | SPP1 Entrez,  Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 5387 | 0.322 | -0.0684 | No |
12 | JUN | JUN Entrez,  Source | jun oncogene | 5515 | 0.296 | -0.0676 | No |
13 | THBS1 | THBS1 Entrez,  Source | thrombospondin 1 | 5629 | 0.278 | -0.0663 | No |
14 | TGIF | TGIF Entrez,  Source | TGFB-induced factor (TALE family homeobox) | 6356 | 0.144 | -0.1159 | No |
15 | EGF | EGF Entrez,  Source | epidermal growth factor (beta-urogastrone) | 6502 | 0.119 | -0.1227 | No |
16 | LIF | LIF Entrez,  Source | leukemia inhibitory factor (cholinergic differentiation factor) | 6625 | 0.095 | -0.1285 | No |
17 | FOS | FOS Entrez,  Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 6898 | 0.046 | -0.1474 | No |
18 | BMP4 | BMP4 Entrez,  Source | bone morphogenetic protein 4 | 7690 | -0.107 | -0.2031 | No |
19 | RUNX3 | RUNX3 Entrez,  Source | runt-related transcription factor 3 | 8404 | -0.245 | -0.2482 | No |
20 | MAPK9 | MAPK9 Entrez,  Source | mitogen-activated protein kinase 9 | 8576 | -0.281 | -0.2512 | No |
21 | TGFBR2 | TGFBR2 Entrez,  Source | transforming growth factor, beta receptor II (70/80kDa) | 8883 | -0.347 | -0.2621 | No |
22 | TNF | TNF Entrez,  Source | tumor necrosis factor (TNF superfamily, member 2) | 8938 | -0.359 | -0.2535 | No |
23 | IFNG | IFNG Entrez,  Source | interferon, gamma | 9074 | -0.388 | -0.2501 | No |
24 | TGFBR3 | TGFBR3 Entrez,  Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 9693 | -0.528 | -0.2781 | No |
25 | ENG | ENG Entrez,  Source | endoglin (Osler-Rendu-Weber syndrome 1) | 11737 | -1.133 | -0.3921 | Yes |
26 | MAPK3 | MAPK3 Entrez,  Source | mitogen-activated protein kinase 3 | 11781 | -1.155 | -0.3548 | Yes |
27 | TFE3 | TFE3 Entrez,  Source | transcription factor binding to IGHM enhancer 3 | 11809 | -1.165 | -0.3160 | Yes |
28 | ZFHX1B | ZFHX1B Entrez,  Source | zinc finger homeobox 1b | 11864 | -1.188 | -0.2784 | Yes |
29 | CTNNB1 | CTNNB1 Entrez,  Source | catenin (cadherin-associated protein), beta 1, 88kDa | 12139 | -1.311 | -0.2530 | Yes |
30 | CREBBP | CREBBP Entrez,  Source | CREB binding protein (Rubinstein-Taybi syndrome) | 12434 | -1.485 | -0.2231 | Yes |
31 | INHBA | INHBA Entrez,  Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 12715 | -1.689 | -0.1849 | Yes |
32 | ITGB6 | ITGB6 Entrez,  Source | integrin, beta 6 | 12941 | -1.887 | -0.1356 | Yes |
33 | STAT3 | STAT3 Entrez,  Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 13103 | -2.124 | -0.0732 | Yes |
34 | RUNX2 | RUNX2 Entrez,  Source | runt-related transcription factor 2 | 13257 | -2.552 | 0.0047 | Yes |