Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | DMT |
GeneSet | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES |
Enrichment Score (ES) | -0.3565637 |
Normalized Enrichment Score (NES) | -1.3213662 |
Nominal p-value | 0.08935361 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | PHF11 | PHF11 Entrez,  Source | PHD finger protein 11 | 1060 | 1.471 | -0.0242 | No |
2 | SAG | SAG Entrez,  Source | S-antigen; retina and pineal gland (arrestin) | 1208 | 1.408 | 0.0179 | No |
3 | AKT3 | AKT3 Entrez,  Source | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 2429 | 0.969 | -0.0374 | No |
4 | PLCG2 | PLCG2 Entrez,  Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 2600 | 0.924 | -0.0153 | No |
5 | AKT1 | AKT1 Entrez,  Source | v-akt murine thymoma viral oncogene homolog 1 | 2869 | 0.853 | -0.0032 | No |
6 | TEC | TEC Entrez,  Source | tec protein tyrosine kinase | 2934 | 0.837 | 0.0236 | No |
7 | FLOT1 | FLOT1 Entrez,  Source | flotillin 1 | 2963 | 0.830 | 0.0528 | No |
8 | DAPP1 | DAPP1 Entrez,  Source | dual adaptor of phosphotyrosine and 3-phosphoinositides | 3012 | 0.820 | 0.0801 | No |
9 | PPP1R13B | PPP1R13B Entrez,  Source | protein phosphatase 1, regulatory (inhibitor) subunit 13B | 5733 | 0.258 | -0.1149 | No |
10 | FOXO3A | FOXO3A Entrez,  Source | forkhead box O3A | 5947 | 0.219 | -0.1226 | No |
11 | CD19 | CD19 Entrez,  Source | CD19 molecule | 6610 | 0.098 | -0.1688 | No |
12 | BCR | BCR Entrez,  Source | breakpoint cluster region | 6681 | 0.086 | -0.1708 | No |
13 | FLOT2 | FLOT2 Entrez,  Source | flotillin 2 | 7542 | -0.078 | -0.2326 | No |
14 | LYN | LYN Entrez,  Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 8057 | -0.179 | -0.2645 | No |
15 | NR0B2 | NR0B2 Entrez,  Source | nuclear receptor subfamily 0, group B, member 2 | 8197 | -0.210 | -0.2670 | No |
16 | PTEN | PTEN Entrez,  Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 8633 | -0.290 | -0.2888 | No |
17 | RPS6KA2 | RPS6KA2 Entrez,  Source | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 9534 | -0.489 | -0.3381 | Yes |
18 | ITPR2 | ITPR2 Entrez,  Source | inositol 1,4,5-triphosphate receptor, type 2 | 9636 | -0.511 | -0.3264 | Yes |
19 | PIK3CA | PIK3CA Entrez,  Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 9953 | -0.585 | -0.3281 | Yes |
20 | VAV1 | VAV1 Entrez,  Source | vav 1 oncogene | 9958 | -0.586 | -0.3063 | Yes |
21 | PITX2 | PITX2 Entrez,  Source | paired-like homeodomain transcription factor 2 | 10012 | -0.597 | -0.2878 | Yes |
22 | SYK | SYK Entrez,  Source | spleen tyrosine kinase | 10054 | -0.608 | -0.2679 | Yes |
23 | ITPR3 | ITPR3 Entrez,  Source | inositol 1,4,5-triphosphate receptor, type 3 | 10111 | -0.621 | -0.2487 | Yes |
24 | BTK | BTK Entrez,  Source | Bruton agammaglobulinemia tyrosine kinase | 10443 | -0.704 | -0.2470 | Yes |
25 | RPS6KB1 | RPS6KB1 Entrez,  Source | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 10627 | -0.758 | -0.2322 | Yes |
26 | RPS6KA1 | RPS6KA1 Entrez,  Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 10673 | -0.770 | -0.2065 | Yes |
27 | ITPR1 | ITPR1 Entrez,  Source | inositol 1,4,5-triphosphate receptor, type 1 | 10812 | -0.808 | -0.1864 | Yes |
28 | PTPRC | PTPRC Entrez,  Source | protein tyrosine phosphatase, receptor type, C | 11048 | -0.881 | -0.1708 | Yes |
29 | CDKN2A | CDKN2A Entrez,  Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 11199 | -0.930 | -0.1470 | Yes |
30 | GAB1 | GAB1 Entrez,  Source | GRB2-associated binding protein 1 | 11359 | -0.988 | -0.1216 | Yes |
31 | AKT2 | AKT2 Entrez,  Source | v-akt murine thymoma viral oncogene homolog 2 | 12561 | -1.566 | -0.1529 | Yes |
32 | PSCD3 | PSCD3 Entrez,  Source | pleckstrin homology, Sec7 and coiled-coil domains 3 | 12580 | -1.578 | -0.0947 | Yes |
33 | PDK1 | PDK1 Entrez,  Source | pyruvate dehydrogenase kinase, isozyme 1 | 12651 | -1.637 | -0.0381 | Yes |
34 | RPS6KA3 | RPS6KA3 Entrez,  Source | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 13205 | -2.342 | 0.0087 | Yes |