DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classDMT
GeneSetRAC1PATHWAY
Enrichment Score (ES)-0.42033005
Normalized Enrichment Score (NES)-1.2849154
Nominal p-value0.1749503
FDR q-value1.0
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: RAC1PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1WASF1WASF1
Entrez,  Source
WAS protein family, member 112501.391-0.0115No
2PPP1R12BPPP1R12B
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12B34060.721-0.1308No
3PLD1PLD1
Entrez,  Source
phospholipase D1, phosphatidylcholine-specific34220.720-0.0892No
4NCF2NCF2
Entrez,  Source
neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)49920.399-0.1835No
5PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide52190.359-0.1792No
6ARFIP2ARFIP2
Entrez,  Source
ADP-ribosylation factor interacting protein 2 (arfaptin 2)53470.332-0.1691No
7CFL1CFL1
Entrez,  Source
cofilin 1 (non-muscle)55550.291-0.1674No
8MYLKMYLK
Entrez,  Source
myosin, light chain kinase59920.211-0.1877No
9RALBP1RALBP1
Entrez,  Source
ralA binding protein 161220.188-0.1862No
10RAC1RAC1
Entrez,  Source
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)67970.064-0.2331No
11PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)7400-0.050-0.2754No
12CDK5R1CDK5R1
Entrez,  Source
cyclin-dependent kinase 5, regulatory subunit 1 (p35)8899-0.351-0.3673No
13MAP3K1MAP3K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase 19304-0.439-0.3716No
14PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide9953-0.585-0.3857Yes
15VAV1VAV1
Entrez,  Source
vav 1 oncogene9958-0.586-0.3512Yes
16RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 110627-0.758-0.3565Yes
17MYL2MYL2
Entrez,  Source
myosin, light chain 2, regulatory, cardiac, slow10890-0.837-0.3265Yes
18CDK5CDK5
Entrez,  Source
cyclin-dependent kinase 512009-1.250-0.3365Yes
19TRIOTRIO
Entrez,  Source
triple functional domain (PTPRF interacting)12495-1.520-0.2828Yes
20PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)12644-1.629-0.1973Yes
21CHN1CHN1
Entrez,  Source
chimerin (chimaerin) 113043-2.020-0.1074Yes
22LIMK1LIMK1
Entrez,  Source
LIM domain kinase 113122-2.1610.0149Yes
Table: GSEA details [plain text format]



Fig 2: RAC1PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: RAC1PATHWAY: Random ES distribution   
Gene set null distribution of ES for RAC1PATHWAY