Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | DMT |
GeneSet | SA_B_CELL_RECEPTOR_COMPLEXES |
Enrichment Score (ES) | -0.46423918 |
Normalized Enrichment Score (NES) | -1.4351326 |
Nominal p-value | 0.077083334 |
FDR q-value | 0.97311074 |
FWER p-Value | 0.987 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | ELK1 | ELK1 Entrez,  Source | ELK1, member of ETS oncogene family | 1077 | 1.464 | 0.0052 | No |
2 | HRAS | HRAS Entrez,  Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 1882 | 1.139 | 0.0118 | No |
3 | VAV2 | VAV2 Entrez,  Source | vav 2 oncogene | 5287 | 0.344 | -0.2239 | No |
4 | JUN | JUN Entrez,  Source | jun oncogene | 5515 | 0.296 | -0.2235 | No |
5 | BCR | BCR Entrez,  Source | breakpoint cluster region | 6681 | 0.086 | -0.3061 | No |
6 | RAC1 | RAC1 Entrez,  Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 6797 | 0.064 | -0.3110 | No |
7 | FOS | FOS Entrez,  Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 6898 | 0.046 | -0.3158 | No |
8 | SHC1 | SHC1 Entrez,  Source | SHC (Src homology 2 domain containing) transforming protein 1 | 7655 | -0.101 | -0.3667 | No |
9 | SOS1 | SOS1 Entrez,  Source | son of sevenless homolog 1 (Drosophila) | 7737 | -0.114 | -0.3661 | No |
10 | VAV3 | VAV3 Entrez,  Source | vav 3 oncogene | 7896 | -0.151 | -0.3691 | No |
11 | LYN | LYN Entrez,  Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 8057 | -0.179 | -0.3705 | No |
12 | MAP3K1 | MAP3K1 Entrez,  Source | mitogen-activated protein kinase kinase kinase 1 | 9304 | -0.439 | -0.4384 | Yes |
13 | GRB2 | GRB2 Entrez,  Source | growth factor receptor-bound protein 2 | 9614 | -0.507 | -0.4318 | Yes |
14 | VAV1 | VAV1 Entrez,  Source | vav 1 oncogene | 9958 | -0.586 | -0.4231 | Yes |
15 | SYK | SYK Entrez,  Source | spleen tyrosine kinase | 10054 | -0.608 | -0.3944 | Yes |
16 | PAPPA | PAPPA Entrez,  Source | pregnancy-associated plasma protein A, pappalysin 1 | 10474 | -0.714 | -0.3838 | Yes |
17 | RPS6KA1 | RPS6KA1 Entrez,  Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 10673 | -0.770 | -0.3534 | Yes |
18 | BLNK | BLNK Entrez,  Source | B-cell linker | 10719 | -0.781 | -0.3107 | Yes |
19 | ATF2 | ATF2 Entrez,  Source | activating transcription factor 2 | 11600 | -1.077 | -0.3135 | Yes |
20 | MAPK1 | MAPK1 Entrez,  Source | mitogen-activated protein kinase 1 | 11721 | -1.127 | -0.2561 | Yes |
21 | MAPK3 | MAPK3 Entrez,  Source | mitogen-activated protein kinase 3 | 11781 | -1.155 | -0.1925 | Yes |
22 | MAP2K1 | MAP2K1 Entrez,  Source | mitogen-activated protein kinase kinase 1 | 11928 | -1.218 | -0.1318 | Yes |
23 | MAPK8IP3 | MAPK8IP3 Entrez,  Source | mitogen-activated protein kinase 8 interacting protein 3 | 12687 | -1.670 | -0.0904 | Yes |
24 | RPS6KA3 | RPS6KA3 Entrez,  Source | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 13205 | -2.342 | 0.0086 | Yes |