Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | DMT |
GeneSet | ST_B_CELL_ANTIGEN_RECEPTOR |
Enrichment Score (ES) | -0.36319393 |
Normalized Enrichment Score (NES) | -1.3560518 |
Nominal p-value | 0.08350305 |
FDR q-value | 1.0 |
FWER p-Value | 0.998 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | NFKBIL1 | NFKBIL1 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | 594 | 1.730 | 0.0141 | No |
2 | ITPKA | ITPKA Entrez,  Source | inositol 1,4,5-trisphosphate 3-kinase A | 1600 | 1.243 | -0.0192 | No |
3 | PIK3CD | PIK3CD Entrez,  Source | phosphoinositide-3-kinase, catalytic, delta polypeptide | 1790 | 1.167 | 0.0062 | No |
4 | AKT3 | AKT3 Entrez,  Source | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 2429 | 0.969 | -0.0088 | No |
5 | PLCG2 | PLCG2 Entrez,  Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 2600 | 0.924 | 0.0098 | No |
6 | AKT1 | AKT1 Entrez,  Source | v-akt murine thymoma viral oncogene homolog 1 | 2869 | 0.853 | 0.0187 | No |
7 | BAD | BAD Entrez,  Source | BCL2-antagonist of cell death | 3213 | 0.770 | 0.0191 | No |
8 | NFKB1 | NFKB1 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 4261 | 0.547 | -0.0412 | No |
9 | CSK | CSK Entrez,  Source | c-src tyrosine kinase | 5260 | 0.351 | -0.1044 | No |
10 | PPP1R13B | PPP1R13B Entrez,  Source | protein phosphatase 1, regulatory (inhibitor) subunit 13B | 5733 | 0.258 | -0.1311 | No |
11 | SERPINA4 | SERPINA4 Entrez,  Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 | 5985 | 0.212 | -0.1428 | No |
12 | CD19 | CD19 Entrez,  Source | CD19 molecule | 6610 | 0.098 | -0.1864 | No |
13 | BCR | BCR Entrez,  Source | breakpoint cluster region | 6681 | 0.086 | -0.1888 | No |
14 | NFKBIA | NFKBIA Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 7246 | -0.021 | -0.2305 | No |
15 | PIK3R1 | PIK3R1 Entrez,  Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 7400 | -0.050 | -0.2404 | No |
16 | NFKBIE | NFKBIE Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 7602 | -0.092 | -0.2524 | No |
17 | SHC1 | SHC1 Entrez,  Source | SHC (Src homology 2 domain containing) transforming protein 1 | 7655 | -0.101 | -0.2529 | No |
18 | SOS1 | SOS1 Entrez,  Source | son of sevenless homolog 1 (Drosophila) | 7737 | -0.114 | -0.2551 | No |
19 | NFAT5 | NFAT5 Entrez,  Source | nuclear factor of activated T-cells 5, tonicity-responsive | 7782 | -0.123 | -0.2542 | No |
20 | LYN | LYN Entrez,  Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 8057 | -0.179 | -0.2687 | No |
21 | MAP2K2 | MAP2K2 Entrez,  Source | mitogen-activated protein kinase kinase 2 | 9313 | -0.442 | -0.3482 | Yes |
22 | RAF1 | RAF1 Entrez,  Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 9350 | -0.450 | -0.3356 | Yes |
23 | PI3 | PI3 Entrez,  Source | peptidase inhibitor 3, skin-derived (SKALP) | 9547 | -0.490 | -0.3336 | Yes |
24 | GRB2 | GRB2 Entrez,  Source | growth factor receptor-bound protein 2 | 9614 | -0.507 | -0.3213 | Yes |
25 | PIK3CA | PIK3CA Entrez,  Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 9953 | -0.585 | -0.3269 | Yes |
26 | VAV1 | VAV1 Entrez,  Source | vav 1 oncogene | 9958 | -0.586 | -0.3073 | Yes |
27 | SYK | SYK Entrez,  Source | spleen tyrosine kinase | 10054 | -0.608 | -0.2937 | Yes |
28 | ITPKB | ITPKB Entrez,  Source | inositol 1,4,5-trisphosphate 3-kinase B | 10169 | -0.634 | -0.2808 | Yes |
29 | BTK | BTK Entrez,  Source | Bruton agammaglobulinemia tyrosine kinase | 10443 | -0.704 | -0.2774 | Yes |
30 | NFKB2 | NFKB2 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 10468 | -0.710 | -0.2550 | Yes |
31 | BLNK | BLNK Entrez,  Source | B-cell linker | 10719 | -0.781 | -0.2472 | Yes |
32 | MAPK1 | MAPK1 Entrez,  Source | mitogen-activated protein kinase 1 | 11721 | -1.127 | -0.2843 | Yes |
33 | EPHB2 | EPHB2 Entrez,  Source | EPH receptor B2 | 11875 | -1.192 | -0.2552 | Yes |
34 | MAP2K1 | MAP2K1 Entrez,  Source | mitogen-activated protein kinase kinase 1 | 11928 | -1.218 | -0.2177 | Yes |
35 | SOS2 | SOS2 Entrez,  Source | son of sevenless homolog 2 (Drosophila) | 11945 | -1.223 | -0.1773 | Yes |
36 | AKT2 | AKT2 Entrez,  Source | v-akt murine thymoma viral oncogene homolog 2 | 12561 | -1.566 | -0.1703 | Yes |
37 | NFKBIB | NFKBIB Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 12821 | -1.781 | -0.1292 | Yes |
38 | DAG1 | DAG1 Entrez,  Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 13133 | -2.182 | -0.0784 | Yes |
39 | NFKBIL2 | NFKBIL2 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 | 13279 | -2.715 | 0.0031 | Yes |