Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | NGT |
GeneSet | P38MAPKPATHWAY |
Enrichment Score (ES) | 0.33228427 |
Normalized Enrichment Score (NES) | 1.2780409 |
Nominal p-value | 0.12598425 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | TGFBR1 | TGFBR1 Entrez,  Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 690 | 1.674 | 0.0062 | Yes |
2 | MAX | MAX Entrez,  Source | MYC associated factor X | 855 | 1.581 | 0.0489 | Yes |
3 | TGFB1 | TGFB1 Entrez,  Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 931 | 1.531 | 0.0964 | Yes |
4 | MEF2C | MEF2C Entrez,  Source | MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) | 1072 | 1.466 | 0.1369 | Yes |
5 | ELK1 | ELK1 Entrez,  Source | ELK1, member of ETS oncogene family | 1077 | 1.464 | 0.1875 | Yes |
6 | PLA2G4A | PLA2G4A Entrez,  Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 1625 | 1.233 | 0.1891 | Yes |
7 | MKNK1 | MKNK1 Entrez,  Source | MAP kinase interacting serine/threonine kinase 1 | 1740 | 1.187 | 0.2218 | Yes |
8 | HRAS | HRAS Entrez,  Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 1882 | 1.139 | 0.2508 | Yes |
9 | TRAF2 | TRAF2 Entrez,  Source | TNF receptor-associated factor 2 | 1966 | 1.112 | 0.2832 | Yes |
10 | MAPKAPK2 | MAPKAPK2 Entrez,  Source | mitogen-activated protein kinase-activated protein kinase 2 | 2012 | 1.098 | 0.3180 | Yes |
11 | STAT1 | STAT1 Entrez,  Source | signal transducer and activator of transcription 1, 91kDa | 2291 | 1.014 | 0.3323 | Yes |
12 | MAP3K9 | MAP3K9 Entrez,  Source | mitogen-activated protein kinase kinase kinase 9 | 2848 | 0.859 | 0.3203 | No |
13 | DDIT3 | DDIT3 Entrez,  Source | DNA-damage-inducible transcript 3 | 3421 | 0.720 | 0.3022 | No |
14 | MAPK14 | MAPK14 Entrez,  Source | mitogen-activated protein kinase 14 | 3795 | 0.637 | 0.2963 | No |
15 | RPS6KA5 | RPS6KA5 Entrez,  Source | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 4441 | 0.512 | 0.2655 | No |
16 | TGFB3 | TGFB3 Entrez,  Source | transforming growth factor, beta 3 | 4502 | 0.503 | 0.2785 | No |
17 | HSPB2 | HSPB2 Entrez,  Source | heat shock 27kDa protein 2 | 4920 | 0.412 | 0.2614 | No |
18 | HMGN1 | HMGN1 Entrez,  Source | high-mobility group nucleosome binding domain 1 | 5668 | 0.269 | 0.2145 | No |
19 | MAPKAPK5 | MAPKAPK5 Entrez,  Source | mitogen-activated protein kinase-activated protein kinase 5 | 5745 | 0.257 | 0.2177 | No |
20 | MEF2A | MEF2A Entrez,  Source | MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) | 5913 | 0.225 | 0.2130 | No |
21 | MAP2K4 | MAP2K4 Entrez,  Source | mitogen-activated protein kinase kinase 4 | 5946 | 0.219 | 0.2182 | No |
22 | MEF2D | MEF2D Entrez,  Source | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 6111 | 0.190 | 0.2124 | No |
23 | TRADD | TRADD Entrez,  Source | TNFRSF1A-associated via death domain | 6703 | 0.083 | 0.1708 | No |
24 | RAC1 | RAC1 Entrez,  Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 6797 | 0.064 | 0.1660 | No |
25 | MAP3K7 | MAP3K7 Entrez,  Source | mitogen-activated protein kinase kinase kinase 7 | 7018 | 0.022 | 0.1502 | No |
26 | RIPK1 | RIPK1 Entrez,  Source | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 7159 | -0.004 | 0.1398 | No |
27 | SHC1 | SHC1 Entrez,  Source | SHC (Src homology 2 domain containing) transforming protein 1 | 7655 | -0.101 | 0.1061 | No |
28 | CREB1 | CREB1 Entrez,  Source | cAMP responsive element binding protein 1 | 8431 | -0.251 | 0.0564 | No |
29 | MYC | MYC Entrez,  Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 8724 | -0.312 | 0.0453 | No |
30 | TGFB2 | TGFB2 Entrez,  Source | transforming growth factor, beta 2 | 9187 | -0.412 | 0.0248 | No |
31 | MAP3K1 | MAP3K1 Entrez,  Source | mitogen-activated protein kinase kinase kinase 1 | 9304 | -0.439 | 0.0313 | No |
32 | GRB2 | GRB2 Entrez,  Source | growth factor receptor-bound protein 2 | 9614 | -0.507 | 0.0257 | No |
33 | CDC42 | CDC42 Entrez,  Source | cell division cycle 42 (GTP binding protein, 25kDa) | 9850 | -0.560 | 0.0274 | No |
34 | MEF2B | MEF2B Entrez,  Source | MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) | 10026 | -0.600 | 0.0351 | No |
35 | HSPB1 | HSPB1 Entrez,  Source | heat shock 27kDa protein 1 | 11017 | -0.873 | -0.0090 | No |
36 | MAP3K5 | MAP3K5 Entrez,  Source | mitogen-activated protein kinase kinase kinase 5 | 11446 | -1.020 | -0.0058 | No |
37 | ATF2 | ATF2 Entrez,  Source | activating transcription factor 2 | 11600 | -1.077 | 0.0201 | No |
38 | MAP2K6 | MAP2K6 Entrez,  Source | mitogen-activated protein kinase kinase 6 | 12382 | -1.450 | 0.0117 | No |
39 | DAXX | DAXX Entrez,  Source | death-associated protein 6 | 12719 | -1.692 | 0.0452 | No |