DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classNGT
GeneSetP38MAPKPATHWAY
Enrichment Score (ES)0.33228427
Normalized Enrichment Score (NES)1.2780409
Nominal p-value0.12598425
FDR q-value1.0
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: P38MAPKPATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1TGFBR1TGFBR1
Entrez,  Source
transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)6901.6740.0062Yes
2MAXMAX
Entrez,  Source
MYC associated factor X8551.5810.0489Yes
3TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)9311.5310.0964Yes
4MEF2CMEF2C
Entrez,  Source
MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)10721.4660.1369Yes
5ELK1ELK1
Entrez,  Source
ELK1, member of ETS oncogene family10771.4640.1875Yes
6PLA2G4APLA2G4A
Entrez,  Source
phospholipase A2, group IVA (cytosolic, calcium-dependent)16251.2330.1891Yes
7MKNK1MKNK1
Entrez,  Source
MAP kinase interacting serine/threonine kinase 117401.1870.2218Yes
8HRASHRAS
Entrez,  Source
v-Ha-ras Harvey rat sarcoma viral oncogene homolog18821.1390.2508Yes
9TRAF2TRAF2
Entrez,  Source
TNF receptor-associated factor 219661.1120.2832Yes
10MAPKAPK2MAPKAPK2
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 220121.0980.3180Yes
11STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa22911.0140.3323Yes
12MAP3K9MAP3K9
Entrez,  Source
mitogen-activated protein kinase kinase kinase 928480.8590.3203No
13DDIT3DDIT3
Entrez,  Source
DNA-damage-inducible transcript 334210.7200.3022No
14MAPK14MAPK14
Entrez,  Source
mitogen-activated protein kinase 1437950.6370.2963No
15RPS6KA5RPS6KA5
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 544410.5120.2655No
16TGFB3TGFB3
Entrez,  Source
transforming growth factor, beta 345020.5030.2785No
17HSPB2HSPB2
Entrez,  Source
heat shock 27kDa protein 249200.4120.2614No
18HMGN1HMGN1
Entrez,  Source
high-mobility group nucleosome binding domain 156680.2690.2145No
19MAPKAPK5MAPKAPK5
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 557450.2570.2177No
20MEF2AMEF2A
Entrez,  Source
MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)59130.2250.2130No
21MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 459460.2190.2182No
22MEF2DMEF2D
Entrez,  Source
MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D)61110.1900.2124No
23TRADDTRADD
Entrez,  Source
TNFRSF1A-associated via death domain67030.0830.1708No
24RAC1RAC1
Entrez,  Source
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)67970.0640.1660No
25MAP3K7MAP3K7
Entrez,  Source
mitogen-activated protein kinase kinase kinase 770180.0220.1502No
26RIPK1RIPK1
Entrez,  Source
receptor (TNFRSF)-interacting serine-threonine kinase 17159-0.0040.1398No
27SHC1SHC1
Entrez,  Source
SHC (Src homology 2 domain containing) transforming protein 17655-0.1010.1061No
28CREB1CREB1
Entrez,  Source
cAMP responsive element binding protein 18431-0.2510.0564No
29MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)8724-0.3120.0453No
30TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 29187-0.4120.0248No
31MAP3K1MAP3K1
Entrez,  Source
mitogen-activated protein kinase kinase kinase 19304-0.4390.0313No
32GRB2GRB2
Entrez,  Source
growth factor receptor-bound protein 29614-0.5070.0257No
33CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)9850-0.5600.0274No
34MEF2BMEF2B
Entrez,  Source
MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B)10026-0.6000.0351No
35HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 111017-0.873-0.0090No
36MAP3K5MAP3K5
Entrez,  Source
mitogen-activated protein kinase kinase kinase 511446-1.020-0.0058No
37ATF2ATF2
Entrez,  Source
activating transcription factor 211600-1.0770.0201No
38MAP2K6MAP2K6
Entrez,  Source
mitogen-activated protein kinase kinase 612382-1.4500.0117No
39DAXXDAXX
Entrez,  Source
death-associated protein 612719-1.6920.0452No
Table: GSEA details [plain text format]



Fig 2: P38MAPKPATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: P38MAPKPATHWAY: Random ES distribution   
Gene set null distribution of ES for P38MAPKPATHWAY