DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classNGT
GeneSetFETAL_LIVER_HS_ENRICHED_TF_JP
Enrichment Score (ES)0.31867695
Normalized Enrichment Score (NES)1.2284639
Nominal p-value0.18052739
FDR q-value1.0
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: FETAL_LIVER_HS_ENRICHED_TF_JP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ZFP64ZFP64
Entrez,  Source
zinc finger protein 64 homolog (mouse)193.0970.0503Yes
2SPOPSPOP
Entrez,  Source
speckle-type POZ protein2672.0980.0667Yes
3RBX1RBX1
Entrez,  Source
ring-box 12752.0880.1011Yes
4GATA2GATA2
Entrez,  Source
GATA binding protein 25461.7570.1101Yes
5RNF7RNF7
Entrez,  Source
ring finger protein 76451.7000.1311Yes
6BRD4BRD4
Entrez,  Source
bromodomain containing 48451.5880.1426Yes
7H2AFY2H2AFY2
Entrez,  Source
H2A histone family, member Y28481.5850.1689Yes
8ZNF435ZNF435
Entrez,  Source
zinc finger protein 4358961.5520.1913Yes
9HDAC1HDAC1
Entrez,  Source
histone deacetylase 110211.4870.2068Yes
10MEF2CMEF2C
Entrez,  Source
MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)10721.4660.2275Yes
11IFI35IFI35
Entrez,  Source
interferon-induced protein 3511171.4460.2484Yes
12EGR1EGR1
Entrez,  Source
early growth response 111301.4400.2715Yes
13HMGB1HMGB1
Entrez,  Source
high-mobility group box 112931.3690.2822Yes
14SIRT2SIRT2
Entrez,  Source
sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)15191.2720.2864Yes
15ELK3ELK3
Entrez,  Source
ELK3, ETS-domain protein (SRF accessory protein 2)15821.2510.3027Yes
16PHC2PHC2
Entrez,  Source
polyhomeotic homolog 2 (Drosophila)16611.2210.3172Yes
17ZNF282ZNF282
Entrez,  Source
zinc finger protein 28220191.0940.3085Yes
18SOX13SOX13
Entrez,  Source
SRY (sex determining region Y)-box 1322761.0190.3062Yes
19STAT5ASTAT5A
Entrez,  Source
signal transducer and activator of transcription 5A23470.9950.3175Yes
20NMINMI
Entrez,  Source
N-myc (and STAT) interactor27160.8910.3046Yes
21SOX15SOX15
Entrez,  Source
SRY (sex determining region Y)-box 1528120.8670.3120Yes
22HMGN2HMGN2
Entrez,  Source
high-mobility group nucleosomal binding domain 229970.8230.3118Yes
23NR1H3NR1H3
Entrez,  Source
nuclear receptor subfamily 1, group H, member 331180.7940.3160Yes
24DDIT3DDIT3
Entrez,  Source
DNA-damage-inducible transcript 334210.7200.3052Yes
25DNMT3BDNMT3B
Entrez,  Source
DNA (cytosine-5-)-methyltransferase 3 beta34950.7020.3115Yes
26MED6MED6
Entrez,  Source
mediator of RNA polymerase II transcription, subunit 6 homolog (S. cerevisiae)35540.6930.3187Yes
27NR2C2NR2C2
Entrez,  Source
nuclear receptor subfamily 2, group C, member 240760.5830.2891No
28NFKB1NFKB1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)42610.5470.2843No
29SP100SP100
Entrez,  Source
SP100 nuclear antigen43110.5370.2896No
30PQBP1PQBP1
Entrez,  Source
polyglutamine binding protein 144960.5040.2841No
31RFXANKRFXANK
Entrez,  Source
regulatory factor X-associated ankyrin-containing protein45670.4880.2870No
32EGR3EGR3
Entrez,  Source
early growth response 347020.4550.2845No
33NSD1NSD1
Entrez,  Source
nuclear receptor binding SET domain protein 149710.4020.2710No
34ELK4ELK4
Entrez,  Source
ELK4, ETS-domain protein (SRF accessory protein 1)49770.4020.2773No
35NRF1NRF1
Entrez,  Source
nuclear respiratory factor 153420.3330.2554No
36PROX1PROX1
Entrez,  Source
prospero-related homeobox 159080.2270.2166No
37MEF2AMEF2A
Entrez,  Source
MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)59130.2250.2200No
38PMF1PMF1
Entrez,  Source
polyamine-modulated factor 159610.2170.2201No
39MLLMLL
Entrez,  Source
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)61340.1870.2102No
40BAZ1BBAZ1B
Entrez,  Source
bromodomain adjacent to zinc finger domain, 1B62530.1650.2041No
41DBPDBP
Entrez,  Source
D site of albumin promoter (albumin D-box) binding protein63080.1540.2026No
42TGIFTGIF
Entrez,  Source
TGFB-induced factor (TALE family homeobox)63560.1440.2014No
43NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 363620.1430.2034No
44DNMT3ADNMT3A
Entrez,  Source
DNA (cytosine-5-)-methyltransferase 3 alpha65810.1040.1887No
45RNF14RNF14
Entrez,  Source
ring finger protein 1467770.0680.1751No
46FOSFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog68980.0460.1668No
47ETV5ETV5
Entrez,  Source
ets variant gene 5 (ets-related molecule)69270.0400.1654No
48RNF4RNF4
Entrez,  Source
ring finger protein 469600.0320.1635No
49ILF2ILF2
Entrez,  Source
interleukin enhancer binding factor 2, 45kDa7389-0.0480.1320No
50SPIBSPIB
Entrez,  Source
Spi-B transcription factor (Spi-1/PU.1 related)7499-0.0690.1249No
51RUNX1RUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)7613-0.0940.1180No
52PHTF1PHTF1
Entrez,  Source
putative homeodomain transcription factor 17832-0.1350.1038No
53ELF1ELF1
Entrez,  Source
E74-like factor 1 (ets domain transcription factor)7907-0.1530.1008No
54MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 37939-0.1590.1011No
55ID4ID4
Entrez,  Source
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein7975-0.1660.1012No
56HIST1H4AHIST1H4A
Entrez,  Source
histone cluster 1, H4a8240-0.2160.0849No
57ETS1ETS1
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)8284-0.2250.0854No
58MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)8724-0.3120.0575No
59HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed8818-0.3320.0560No
60SRFSRF
Entrez,  Source
serum response factor (c-fos serum response element-binding transcription factor)9361-0.4530.0226No
61EVI1EVI1
Entrez,  Source
ecotropic viral integration site 19553-0.4920.0164No
62GTF2IRD1GTF2IRD1
Entrez,  Source
GTF2I repeat domain containing 19763-0.5420.0097No
63ZNF238ZNF238
Entrez,  Source
zinc finger protein 23810093-0.616-0.0048No
64SMARCD1SMARCD1
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 110368-0.683-0.0141No
65H2AFZH2AFZ
Entrez,  Source
H2A histone family, member Z10437-0.702-0.0075No
66TCERG1TCERG1
Entrez,  Source
transcription elongation regulator 110588-0.748-0.0063No
67FOSBFOSB
Entrez,  Source
FBJ murine osteosarcoma viral oncogene homolog B10773-0.795-0.0070No
68MDFIMDFI
Entrez,  Source
MyoD family inhibitor11089-0.890-0.0159No
69HLFHLF
Entrez,  Source
hepatic leukemia factor11527-1.050-0.0313No
70FOXO1AFOXO1A
Entrez,  Source
forkhead box O1A (rhabdomyosarcoma)11720-1.126-0.0270No
71TFE3TFE3
Entrez,  Source
transcription factor binding to IGHM enhancer 311809-1.165-0.0142No
72HTATIPHTATIP
Entrez,  Source
HIV-1 Tat interacting protein, 60kDa11957-1.229-0.0047No
73UBTFUBTF
Entrez,  Source
upstream binding transcription factor, RNA polymerase I12179-1.3340.0009No
74SPI1SPI1
Entrez,  Source
spleen focus forming virus (SFFV) proviral integration oncogene spi113189-2.292-0.0370No
75GFI1GFI1
Entrez,  Source
growth factor independent 113291-2.8010.0022No
Table: GSEA details [plain text format]



Fig 2: FETAL_LIVER_HS_ENRICHED_TF_JP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: FETAL_LIVER_HS_ENRICHED_TF_JP: Random ES distribution   
Gene set null distribution of ES for FETAL_LIVER_HS_ENRICHED_TF_JP