DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classDMT
GeneSetPITX2PATHWAY
Enrichment Score (ES)-0.5558175
Normalized Enrichment Score (NES)-1.4590697
Nominal p-value0.08982036
FDR q-value0.99743736
FWER p-Value0.976
Table: GSEA Results Summary



Fig 1: Enrichment plot: PITX2PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1HDAC1HDAC1
Entrez,  Source
histone deacetylase 110211.4870.0127No
2WNT1WNT1
Entrez,  Source
wingless-type MMTV integration site family, member 126740.902-0.0571No
3FZD1FZD1
Entrez,  Source
frizzled homolog 1 (Drosophila)27110.893-0.0062No
4LEF1LEF1
Entrez,  Source
lymphoid enhancer-binding factor 148990.414-0.1456No
5PPARBPPPARBP
Entrez,  Source
PPAR binding protein7225-0.015-0.3194No
6GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta7477-0.065-0.3344No
7LDB1LDB1
Entrez,  Source
LIM domain binding 19197-0.415-0.4386No
8PITX2PITX2
Entrez,  Source
paired-like homeodomain transcription factor 210012-0.597-0.4639No
9AXIN1AXIN1
Entrez,  Source
axin 111236-0.943-0.4991Yes
10HTATIPHTATIP
Entrez,  Source
HIV-1 Tat interacting protein, 60kDa11957-1.229-0.4793Yes
11CTNNB1CTNNB1
Entrez,  Source
catenin (cadherin-associated protein), beta 1, 88kDa12139-1.311-0.4140Yes
12DVL1DVL1
Entrez,  Source
dishevelled, dsh homolog 1 (Drosophila)12295-1.403-0.3412Yes
13TRRAPTRRAP
Entrez,  Source
transformation/transcription domain-associated protein12387-1.453-0.2606Yes
14CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)12434-1.485-0.1748Yes
15EP300EP300
Entrez,  Source
E1A binding protein p30012582-1.579-0.0908Yes
16APCAPC
Entrez,  Source
adenomatosis polyposis coli13227-2.4300.0070Yes
Table: GSEA details [plain text format]



Fig 2: PITX2PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PITX2PATHWAY: Random ES distribution   
Gene set null distribution of ES for PITX2PATHWAY