DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classDMT
GeneSetMCALPAINPATHWAY
Enrichment Score (ES)-0.47667816
Normalized Enrichment Score (NES)-1.4912983
Nominal p-value0.05212355
FDR q-value1.0
FWER p-Value0.96
Table: GSEA Results Summary



Fig 1: Enrichment plot: MCALPAINPATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1HRASHRAS
Entrez,  Source
v-Ha-ras Harvey rat sarcoma viral oncogene homolog18821.139-0.0745No
2CAPN2CAPN2
Entrez,  Source
calpain 2, (m/II) large subunit35230.698-0.1568No
3PRKAR2BPRKAR2B
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type II, beta37330.651-0.1342No
4PRKAR2APRKAR2A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type II, alpha47240.450-0.1821No
5PXNPXN
Entrez,  Source
paxillin52630.351-0.2019No
6PRKACGPRKACG
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, gamma54240.313-0.1955No
7EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)58800.233-0.2160No
8MYLKMYLK
Entrez,  Source
myosin, light chain kinase59920.211-0.2120No
9PRKACBPRKACB
Entrez,  Source
protein kinase, cAMP-dependent, catalytic, beta59980.210-0.2000No
10TLN1TLN1
Entrez,  Source
talin 162190.171-0.2065No
11EGFEGF
Entrez,  Source
epidermal growth factor (beta-urogastrone)65020.119-0.2207No
12PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 28233-0.216-0.3381No
13CXCR3CXCR3
Entrez,  Source
chemokine (C-X-C motif) receptor 39375-0.456-0.3970No
14VIL2VIL2
Entrez,  Source
villin 2 (ezrin)10435-0.700-0.4355Yes
15ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle10699-0.776-0.4096Yes
16MYL2MYL2
Entrez,  Source
myosin, light chain 2, regulatory, cardiac, slow10890-0.837-0.3746Yes
17ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)11447-1.020-0.3564Yes
18CAPN1CAPN1
Entrez,  Source
calpain 1, (mu/I) large subunit11691-1.113-0.3091Yes
19MAPK1MAPK1
Entrez,  Source
mitogen-activated protein kinase 111721-1.127-0.2450Yes
20MAPK3MAPK3
Entrez,  Source
mitogen-activated protein kinase 311781-1.155-0.1815Yes
21PRKAR1APRKAR1A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)13252-2.521-0.1436Yes
22CAPNS1CAPNS1
Entrez,  Source
calpain, small subunit 113253-2.5270.0050Yes
Table: GSEA details [plain text format]



Fig 2: MCALPAINPATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: MCALPAINPATHWAY: Random ES distribution   
Gene set null distribution of ES for MCALPAINPATHWAY