Dataset | Diabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT |
Phenotype | Diabetes.cls#NGT_versus_DMT |
Upregulated in class | NGT |
GeneSet | ELECTRON_TRANSPORT_CHAIN |
Enrichment Score (ES) | 0.6074125 |
Normalized Enrichment Score (NES) | 1.739312 |
Nominal p-value | 0.033797216 |
FDR q-value | 0.2114812 |
FWER p-Value | 0.481 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | NDUFA2 | NDUFA2 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa | 71 | 2.640 | 0.0241 | Yes |
2 | NDUFB2 | NDUFB2 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 82 | 2.575 | 0.0521 | Yes |
3 | COX7A1 | COX7A1 Entrez,  Source | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 97 | 2.506 | 0.0790 | Yes |
4 | ATP5O | ATP5O Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 155 | 2.285 | 0.1002 | Yes |
5 | NDUFB6 | NDUFB6 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 167 | 2.251 | 0.1244 | Yes |
6 | ATP5E | ATP5E Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | 181 | 2.232 | 0.1484 | Yes |
7 | NDUFS5 | NDUFS5 Entrez,  Source | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 216 | 2.167 | 0.1700 | Yes |
8 | NDUFB1 | NDUFB1 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 234 | 2.143 | 0.1926 | Yes |
9 | NDUFB8 | NDUFB8 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 250 | 2.117 | 0.2151 | Yes |
10 | COX7C | COX7C Entrez,  Source | cytochrome c oxidase subunit VIIc | 289 | 2.060 | 0.2352 | Yes |
11 | UQCR | UQCR Entrez,  Source | ubiquinol-cytochrome c reductase, 6.4kDa subunit | 301 | 2.030 | 0.2570 | Yes |
12 | ATP5L | ATP5L Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G | 310 | 2.022 | 0.2790 | Yes |
13 | COX7B | COX7B Entrez,  Source | cytochrome c oxidase subunit VIIb | 323 | 2.001 | 0.3004 | Yes |
14 | ATP5I | ATP5I Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E | 365 | 1.944 | 0.3190 | Yes |
15 | ATP5S | ATP5S Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) | 369 | 1.939 | 0.3404 | Yes |
16 | NDUFA7 | NDUFA7 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 383 | 1.913 | 0.3607 | Yes |
17 | COX7A2 | COX7A2 Entrez,  Source | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 480 | 1.811 | 0.3737 | Yes |
18 | NDUFA10 | NDUFA10 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 769 | 1.625 | 0.3701 | Yes |
19 | NDUFS6 | NDUFS6 Entrez,  Source | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 826 | 1.597 | 0.3837 | Yes |
20 | NDUFS8 | NDUFS8 Entrez,  Source | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 863 | 1.576 | 0.3985 | Yes |
21 | UQCRB | UQCRB Entrez,  Source | ubiquinol-cytochrome c reductase binding protein | 909 | 1.542 | 0.4123 | Yes |
22 | COX6C | COX6C Entrez,  Source | cytochrome c oxidase subunit VIc | 929 | 1.532 | 0.4280 | Yes |
23 | NDUFA6 | NDUFA6 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 955 | 1.516 | 0.4430 | Yes |
24 | NDUFC1 | NDUFC1 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 962 | 1.513 | 0.4595 | Yes |
25 | COX7A2L | COX7A2L Entrez,  Source | cytochrome c oxidase subunit VIIa polypeptide 2 like | 1002 | 1.494 | 0.4732 | Yes |
26 | NDUFA3 | NDUFA3 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 1018 | 1.488 | 0.4886 | Yes |
27 | ATP5H | ATP5H Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 1089 | 1.456 | 0.4996 | Yes |
28 | ATP5J2 | ATP5J2 Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 | 1097 | 1.454 | 0.5153 | Yes |
29 | SLC25A5 | SLC25A5 Entrez,  Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 1153 | 1.431 | 0.5271 | Yes |
30 | NDUFB5 | NDUFB5 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 1181 | 1.422 | 0.5409 | Yes |
31 | NDUFAB1 | NDUFAB1 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 1368 | 1.336 | 0.5418 | Yes |
32 | COX6A1 | COX6A1 Entrez,  Source | cytochrome c oxidase subunit VIa polypeptide 1 | 1395 | 1.326 | 0.5546 | Yes |
33 | NDUFA8 | NDUFA8 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 1559 | 1.257 | 0.5563 | Yes |
34 | ATP5F1 | ATP5F1 Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 | 1595 | 1.245 | 0.5676 | Yes |
35 | COX4I1 | COX4I1 Entrez,  Source | cytochrome c oxidase subunit IV isoform 1 | 1901 | 1.134 | 0.5572 | Yes |
36 | NDUFS7 | NDUFS7 Entrez,  Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 1980 | 1.109 | 0.5637 | Yes |
37 | SDHB | SDHB Entrez,  Source | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 2043 | 1.088 | 0.5711 | Yes |
38 | NDUFA4 | NDUFA4 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa | 2051 | 1.086 | 0.5827 | Yes |
39 | COX11 | COX11 Entrez,  Source | COX11 homolog, cytochrome c oxidase assembly protein (yeast) | 2164 | 1.053 | 0.5860 | Yes |
40 | ATP5D | ATP5D Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 2225 | 1.034 | 0.5930 | Yes |
41 | ATPIF1 | ATPIF1 Entrez,  Source | ATPase inhibitory factor 1 | 2330 | 1.001 | 0.5963 | Yes |
42 | UQCRH | UQCRH Entrez,  Source | ubiquinol-cytochrome c reductase hinge protein | 2395 | 0.977 | 0.6024 | Yes |
43 | NDUFS4 | NDUFS4 Entrez,  Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 2477 | 0.956 | 0.6069 | Yes |
44 | COX5B | COX5B Entrez,  Source | cytochrome c oxidase subunit Vb | 2818 | 0.866 | 0.5909 | Yes |
45 | SDHC | SDHC Entrez,  Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 2861 | 0.855 | 0.5973 | Yes |
46 | NDUFB7 | NDUFB7 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 2912 | 0.842 | 0.6029 | Yes |
47 | UQCRFS1 | UQCRFS1 Entrez,  Source | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 3010 | 0.820 | 0.6047 | Yes |
48 | NDUFB3 | NDUFB3 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 3094 | 0.803 | 0.6074 | Yes |
49 | SLC25A14 | SLC25A14 Entrez,  Source | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 3255 | 0.760 | 0.6038 | No |
50 | NDUFV2 | NDUFV2 Entrez,  Source | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 3404 | 0.721 | 0.6007 | No |
51 | SLC25A6 | SLC25A6 Entrez,  Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 3736 | 0.650 | 0.5829 | No |
52 | ATP5G3 | ATP5G3 Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 3803 | 0.635 | 0.5850 | No |
53 | NDUFV1 | NDUFV1 Entrez,  Source | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 3867 | 0.621 | 0.5872 | No |
54 | SURF1 | SURF1 Entrez,  Source | surfeit 1 | 3891 | 0.618 | 0.5924 | No |
55 | AFG3L2 | AFG3L2 Entrez,  Source | AFG3 ATPase family gene 3-like 2 (yeast) | 3947 | 0.608 | 0.5950 | No |
56 | ATP5G1 | ATP5G1 Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) | 3978 | 0.603 | 0.5995 | No |
57 | ATP5J | ATP5J Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | 4086 | 0.581 | 0.5979 | No |
58 | CYCS | CYCS Entrez,  Source | cytochrome c, somatic | 4178 | 0.562 | 0.5973 | No |
59 | COX5A | COX5A Entrez,  Source | cytochrome c oxidase subunit Va | 4513 | 0.497 | 0.5776 | No |
60 | ATP5C1 | ATP5C1 Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 4517 | 0.497 | 0.5829 | No |
61 | COX15 | COX15 Entrez,  Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 5180 | 0.365 | 0.5370 | No |
62 | NDUFS2 | NDUFS2 Entrez,  Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 5580 | 0.287 | 0.5101 | No |
63 | NDUFS3 | NDUFS3 Entrez,  Source | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 5710 | 0.262 | 0.5032 | No |
64 | NDUFA5 | NDUFA5 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa | 5773 | 0.252 | 0.5014 | No |
65 | NDUFA9 | NDUFA9 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 6198 | 0.174 | 0.4713 | No |
66 | SDHD | SDHD Entrez,  Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 6583 | 0.103 | 0.4434 | No |
67 | UQCRC2 | UQCRC2 Entrez,  Source | ubiquinol-cytochrome c reductase core protein II | 6624 | 0.095 | 0.4415 | No |
68 | NDUFC2 | NDUFC2 Entrez,  Source | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa | 7516 | -0.073 | 0.3750 | No |
69 | POPDC2 | POPDC2 Entrez,  Source | popeye domain containing 2 | 7620 | -0.096 | 0.3683 | No |
70 | NDUFS1 | NDUFS1 Entrez,  Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 7828 | -0.134 | 0.3542 | No |
71 | UCP1 | UCP1 Entrez,  Source | uncoupling protein 1 (mitochondrial, proton carrier) | 7854 | -0.139 | 0.3538 | No |
72 | ATP5G2 | ATP5G2 Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 7914 | -0.154 | 0.3511 | No |
73 | ATP5B | ATP5B Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 8037 | -0.176 | 0.3438 | No |
74 | SLC25A4 | SLC25A4 Entrez,  Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 8562 | -0.278 | 0.3074 | No |
75 | SDHA | SDHA Entrez,  Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 8570 | -0.280 | 0.3100 | No |
76 | UCP3 | UCP3 Entrez,  Source | uncoupling protein 3 (mitochondrial, proton carrier) | 8618 | -0.288 | 0.3096 | No |
77 | COX6A2 | COX6A2 Entrez,  Source | cytochrome c oxidase subunit VIa polypeptide 2 | 9081 | -0.391 | 0.2791 | No |
78 | UCP2 | UCP2 Entrez,  Source | uncoupling protein 2 (mitochondrial, proton carrier) | 10921 | -0.845 | 0.1496 | No |
79 | UQCRC1 | UQCRC1 Entrez,  Source | ubiquinol-cytochrome c reductase core protein I | 11184 | -0.926 | 0.1402 | No |
80 | ATP5A1 | ATP5A1 Entrez,  Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 12943 | -1.888 | 0.0285 | No |