DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classDMT
GeneSetST_B_CELL_ANTIGEN_RECEPTOR
Enrichment Score (ES)-0.36319393
Normalized Enrichment Score (NES)-1.3560518
Nominal p-value0.08350305
FDR q-value1.0
FWER p-Value0.998
Table: GSEA Results Summary



Fig 1: Enrichment plot: ST_B_CELL_ANTIGEN_RECEPTOR   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NFKBIL1NFKBIL1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 15941.7300.0141No
2ITPKAITPKA
Entrez,  Source
inositol 1,4,5-trisphosphate 3-kinase A16001.243-0.0192No
3PIK3CDPIK3CD
Entrez,  Source
phosphoinositide-3-kinase, catalytic, delta polypeptide17901.1670.0062No
4AKT3AKT3
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)24290.969-0.0088No
5PLCG2PLCG2
Entrez,  Source
phospholipase C, gamma 2 (phosphatidylinositol-specific)26000.9240.0098No
6AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 128690.8530.0187No
7BADBAD
Entrez,  Source
BCL2-antagonist of cell death32130.7700.0191No
8NFKB1NFKB1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)42610.547-0.0412No
9CSKCSK
Entrez,  Source
c-src tyrosine kinase52600.351-0.1044No
10PPP1R13BPPP1R13B
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 13B57330.258-0.1311No
11SERPINA4SERPINA4
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 459850.212-0.1428No
12CD19CD19
Entrez,  Source
CD19 molecule66100.098-0.1864No
13BCRBCR
Entrez,  Source
breakpoint cluster region66810.086-0.1888No
14NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha7246-0.021-0.2305No
15PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)7400-0.050-0.2404No
16NFKBIENFKBIE
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon7602-0.092-0.2524No
17SHC1SHC1
Entrez,  Source
SHC (Src homology 2 domain containing) transforming protein 17655-0.101-0.2529No
18SOS1SOS1
Entrez,  Source
son of sevenless homolog 1 (Drosophila)7737-0.114-0.2551No
19NFAT5NFAT5
Entrez,  Source
nuclear factor of activated T-cells 5, tonicity-responsive7782-0.123-0.2542No
20LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog8057-0.179-0.2687No
21MAP2K2MAP2K2
Entrez,  Source
mitogen-activated protein kinase kinase 29313-0.442-0.3482Yes
22RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 19350-0.450-0.3356Yes
23PI3PI3
Entrez,  Source
peptidase inhibitor 3, skin-derived (SKALP)9547-0.490-0.3336Yes
24GRB2GRB2
Entrez,  Source
growth factor receptor-bound protein 29614-0.507-0.3213Yes
25PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide9953-0.585-0.3269Yes
26VAV1VAV1
Entrez,  Source
vav 1 oncogene9958-0.586-0.3073Yes
27SYKSYK
Entrez,  Source
spleen tyrosine kinase10054-0.608-0.2937Yes
28ITPKBITPKB
Entrez,  Source
inositol 1,4,5-trisphosphate 3-kinase B10169-0.634-0.2808Yes
29BTKBTK
Entrez,  Source
Bruton agammaglobulinemia tyrosine kinase10443-0.704-0.2774Yes
30NFKB2NFKB2
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)10468-0.710-0.2550Yes
31BLNKBLNK
Entrez,  Source
B-cell linker10719-0.781-0.2472Yes
32MAPK1MAPK1
Entrez,  Source
mitogen-activated protein kinase 111721-1.127-0.2843Yes
33EPHB2EPHB2
Entrez,  Source
EPH receptor B211875-1.192-0.2552Yes
34MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 111928-1.218-0.2177Yes
35SOS2SOS2
Entrez,  Source
son of sevenless homolog 2 (Drosophila)11945-1.223-0.1773Yes
36AKT2AKT2
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 212561-1.566-0.1703Yes
37NFKBIBNFKBIB
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta12821-1.781-0.1292Yes
38DAG1DAG1
Entrez,  Source
dystroglycan 1 (dystrophin-associated glycoprotein 1)13133-2.182-0.0784Yes
39NFKBIL2NFKBIL2
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 213279-2.7150.0031Yes
Table: GSEA details [plain text format]



Fig 2: ST_B_CELL_ANTIGEN_RECEPTOR   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ST_B_CELL_ANTIGEN_RECEPTOR: Random ES distribution   
Gene set null distribution of ES for ST_B_CELL_ANTIGEN_RECEPTOR