DatasetDiabetes_hgu133a_collapsed_to_symbols.Diabetes.cls#NGT_versus_DMT
PhenotypeDiabetes.cls#NGT_versus_DMT
Upregulated in classNGT
GeneSetDEATHPATHWAY
Enrichment Score (ES)0.33415848
Normalized Enrichment Score (NES)1.2371333
Nominal p-value0.15831663
FDR q-value1.0
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: DEATHPATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1BIDBID
Entrez,  Source
BH3 interacting domain death agonist3701.9380.0748Yes
2BIRC3BIRC3
Entrez,  Source
baculoviral IAP repeat-containing 39931.4990.1074Yes
3TNFSF10TNFSF10
Entrez,  Source
tumor necrosis factor (ligand) superfamily, member 1016661.2190.1214Yes
4FADDFADD
Entrez,  Source
Fas (TNFRSF6)-associated via death domain18671.1410.1668Yes
5TRAF2TRAF2
Entrez,  Source
TNF receptor-associated factor 219661.1120.2183Yes
6DFFADFFA
Entrez,  Source
DNA fragmentation factor, 45kDa, alpha polypeptide29580.8310.1878Yes
7GAS2GAS2
Entrez,  Source
growth arrest-specific 232190.7680.2089Yes
8CASP9CASP9
Entrez,  Source
caspase 9, apoptosis-related cysteine peptidase35090.7010.2242Yes
9CASP3CASP3
Entrez,  Source
caspase 3, apoptosis-related cysteine peptidase38090.6340.2353Yes
10BIRC2BIRC2
Entrez,  Source
baculoviral IAP repeat-containing 238480.6240.2655Yes
11CYCSCYCS
Entrez,  Source
cytochrome c, somatic41780.5620.2705Yes
12NFKB1NFKB1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)42610.5470.2933Yes
13MAP3K14MAP3K14
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1443550.5280.3143Yes
14BIRC4BIRC4
Entrez,  Source
baculoviral IAP repeat-containing 447210.4510.3107Yes
15CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator47260.4490.3342Yes
16CASP6CASP6
Entrez,  Source
caspase 6, apoptosis-related cysteine peptidase50520.3900.3303No
17BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 256710.2680.2980No
18LMNALMNA
Entrez,  Source
lamin A/C59140.2250.2917No
19TNFRSF10BTNFRSF10B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 10b64250.1310.2603No
20TRADDTRADD
Entrez,  Source
TNFRSF1A-associated via death domain67030.0830.2438No
21APAF1APAF1
Entrez,  Source
apoptotic peptidase activating factor68570.0530.2351No
22DFFBDFFB
Entrez,  Source
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)69030.0440.2340No
23RIPK1RIPK1
Entrez,  Source
receptor (TNFRSF)-interacting serine-threonine kinase 17159-0.0040.2150No
24NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha7246-0.0210.2097No
25CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase7519-0.0740.1931No
26RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)8023-0.1740.1645No
27CASP7CASP7
Entrez,  Source
caspase 7, apoptosis-related cysteine peptidase8577-0.2810.1378No
28CHUKCHUK
Entrez,  Source
conserved helix-loop-helix ubiquitous kinase8877-0.3460.1336No
29TNFSF12TNFSF12
Entrez,  Source
tumor necrosis factor (ligand) superfamily, member 129503-0.4810.1120No
30SPTAN1SPTAN1
Entrez,  Source
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)10479-0.7150.0765No
31CASP10CASP10
Entrez,  Source
caspase 10, apoptosis-related cysteine peptidase11336-0.9770.0638No
32TNFRSF25TNFRSF25
Entrez,  Source
tumor necrosis factor receptor superfamily, member 2512619-1.6120.0528No
Table: GSEA details [plain text format]



Fig 2: DEATHPATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: DEATHPATHWAY: Random ES distribution   
Gene set null distribution of ES for DEATHPATHWAY